Vaxcyte has developed a method for producing immunogenic compositions using non-natural amino acids for efficient antigen presentation. The patent includes a claim for a composition containing distinct carrier protein-antigen conjugates for various Streptococcus pneumoniae serotypes, enhancing immune response. GlobalData’s report on Vaxcyte gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on Vaxcyte, LPS antibody-based anti-bacterials was a key innovation area identified from patents. Vaxcyte's grant share as of May 2024 was 1%. Grant share is based on the ratio of number of grants to total number of patents.
Patent granted for immunogenic compositions containing non-natural amino acids
A recently granted patent (Publication Number: US11998599B2) discloses a composition comprising at least 21 distinct crosslinked carrier protein-antigen conjugates. Each conjugate includes a specific serotype of a capsular polysaccharide antigen from Streptococcus pneumoniae, with a total of 21 serotypes covered. The carrier protein in the composition contains T-cell activating epitopes and specific non-natural amino acids, ensuring effective conjugation with the capsular polysaccharide antigens.
Furthermore, the patent details the specific composition variations, including the number of distinct crosslinked carrier protein-antigen conjugates required for different Streptococcus pneumoniae serotypes. The composition also specifies the overall weight ratio of serotype polysaccharides to carrier protein, ensuring optimal effectiveness. Additionally, the patent mentions the presence of less than 25% total free capsular polysaccharide in the composition, highlighting the precise formulation and conjugation methods employed to create this novel vaccine composition.
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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies
