VIS-171 is under clinical development by Visterra and currently in Phase I for Autoimmune Disorders. According to GlobalData, Phase I drugs for Autoimmune Disorders have a 74% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how VIS-171’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

VIS-171 overview

VIS-171 is under development for the treatment of autoimmune diseases. The therapeutic candidate is administered through subcutaneous route. It acts by targeting interleukin 2 receptor (IL2R). 
It was also under development for the treatment of Graft Versus Host Disease (GVHD),lupus nephritis, membranous glomerulonephritis.

Visterra overview

Visterra, formerly Parasol Therapeutics is a clinical-stage biopharmaceutical company that develops antibody therapies for the treatment of infectious diseases. The company’s pipeline products include VIS410, a monoclonal antibody designed to treat influenza A; VIS513, monoclonal antibody for the treatment of dengue; and VIS649, an anti-APRIL monoclonal antibody (mAb) for the treatment of Imumuglobulin A Nephropathy (IgAN). Visterra utilizes its hierotope platform to design and engineer antibody-based therapies that target specific regions and epitopes of pathogens. The company’s technology is based on the atomic interaction network analysis that supports in identifying hierotopes. Visterra is headquartered in Cambridge, Massachusetts, the US.

For a complete picture of VIS-171’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 2 September 2023

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.