Zasocitinib is a small molecule commercialized by Takeda Pharmaceutical, with a leading Phase III program in Plaque Psoriasis (Psoriasis Vulgaris). According to Globaldata, it is involved in 19 clinical trials, of which 11 were completed, 6 are ongoing, and 2 are planned. GlobalData uses proprietary data and analytics to provide a complete picture of Zasocitinib’s valuation in its risk-adjusted NPV model (rNPV). Buy the model here.
The revenue for Zasocitinib is expected to reach an annual total of $79 mn by 2035 in the US based off GlobalData’s Expiry Model. The drug’s revenue forecasts along with estimated costs are used to measure the value of an investment opportunity in that drug, otherwise known as net present value (NPV). Applying the drug’s phase transition success rate to remaining R&D costs and likelihood of approval (LoA) to sales related costs provides a risk-adjusted NPV model (rNPV). The rNPV model is a more conservative valuation measure that accounts for the risk of a drug in clinical development failing to progress.
Zasocitinib Overview
Zasocitinib is under development for the treatment of moderate to severe plaque psoriasis, psoriatic arthritis, generalized pustular psoriasis, erythrodermic psoriasis, inflammatory bowel disease (IBD) including Crohn's disease (regional enteritis), ulcerative colitis and systemic lupus erythematosus. The drug candidate acts by targeting nonreceptor tyrosine protein kinase (TYK2). It is administered through oral route in the form of capsules and tablets.
Takeda Pharmaceutical Overview
Takeda Pharmaceutical (Takeda) is a global pharmaceutical company primarily engaged in the research, development, production, and commercialization of biopharmaceutical products. It provides treatment for inflammatory bowel disease, acid-related diseases, motility disorders and liver diseases; hemophilia and hereditary bleeding disorders; primary immunodeficiency and multifocal motor neuropathy; major depressive disorder and attention-deficit hyperactivity disorder; and its cancer treatment encompasses multiple myeloma, mantle cell lymphoma, non-small cell lung cancer and chronic myeloid leukemia. While the company markets its pharmaceutical products directly, it also collaborates with marketing alliance partners in worldwide. Takeda operates in various countries worldwide, including Japan, the US, Europe, Latin America, Africa, the Middle East, and the Asia Pacific region. Takeda is headquartered in Tokyo, Japan.
The company reported revenues of (Yen) JPY4,263,762 million for the fiscal year ended March 2024 (FY2024), an increase of 5.9% over FY2023. In FY2024, the company’s operating margin was 5.8%, compared to an operating margin of 13.2% in FY2023. In FY2024, the company recorded a net margin of 3.4%, compared to a net margin of 7.9% in FY2023.
The company reported revenues of JPY1,207,990 million for the first quarter ended June 2024, an increase of 15% over the previous quarter.
For a complete picture of Zasocitinib’s valuation, buy the drug’s risk-adjusted NPV model (rNPV) here.
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