Zasocitinib is a small molecule commercialized by Takeda Pharmaceutical, with a leading Phase III program in Plaque Psoriasis (Psoriasis Vulgaris). According to Globaldata, it is involved in 18 clinical trials, of which 9 were completed, 7 are ongoing, and 2 are planned. GlobalData uses proprietary data and analytics to provide a complete picture of Zasocitinibs valuation in its risk-adjusted NPV model (rNPV). Buy the model here.
Smarter leaders trust GlobalData
The revenue for Zasocitinib is expected to reach an annual total of $301 mn by 2035 in the US based off GlobalDatas Expiry Model. The drugs revenue forecasts along with estimated costs are used to measure the value of an investment opportunity in that drug, otherwise known as net present value (NPV). Applying the drugs phase transition success rate to remaining R&D costs and likelihood of approval (LoA) to sales related costs provides a risk-adjusted NPV model (rNPV). The rNPV model is a more conservative valuation measure that accounts for the risk of a drug in clinical development failing to progress.
Zasocitinib Overview
Zasocitinib is under development for the treatment of moderate to severe plaque psoriasis, psoriatic arthritis, generalized pustular psoriasis, erythrodermic psoriasis, inflammatory bowel disease (IBD) including Crohn's disease (regional enteritis), ulcerative colitis and systemic lupus erythematosus. The drug candidate acts by targeting nonreceptor tyrosine protein kinase (TYK2). It is administered through oral route in the form of capsules and tablets.
Takeda Pharmaceutical Overview
Takeda Pharmaceutical (Takeda) is a global pharmaceutical company primarily engaged in the research, development, production, and commercialization of biopharmaceutical products. It provides treatment for inflammatory bowel disease, acid-related diseases, motility disorders and liver diseases; hemophilia and hereditary bleeding disorders; primary immunodeficiency and multifocal motor neuropathy; major depressive disorder and attention-deficit hyperactivity disorder; and its cancer treatment encompasses multiple myeloma, mantle cell lymphoma, non-small cell lung cancer and chronic myeloid leukemia. While the company markets its pharmaceutical products directly, it also collaborates with marketing alliance partners in worldwide. Takeda operates in various countries worldwide, including Japan, the US, Europe, Latin America, Africa, the Middle East, and the Asia Pacific region. Takeda is headquartered in Tokyo, Japan.
The company reported revenues of (Yen) JPY4,263,762 million for the fiscal year ended March 2024 (FY2024), an increase of 5.9% over FY2023. In FY2024, the companys operating margin was 5.8%, compared to an operating margin of 13.2% in FY2023. In FY2024, the company recorded a net margin of 3.4%, compared to a net margin of 7.9% in FY2023.
For a complete picture of Zasocitinibs valuation, buy the drugs risk-adjusted NPV model (rNPV) here.
Data Insights
From
The gold standard of business intelligence.
Blending expert knowledge with cutting-edge technology, GlobalData’s unrivalled proprietary data will enable you to decode what’s happening in your market. You can make better informed decisions and gain a future-proof advantage over your competitors.
GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
To create this model, GlobalData takes into account factors including patent law, known and projected regulatory approval processes, cash flows, drug margins and company expenses. Combining these data points with GlobalData’s world class analysis creates high value models that companies can use to help in evaluation processes for each drug or company.
The rNPV method integrates the probability of a drug reaching a clinical stage into the cash flow at that time, which provides a more accurate valuation, as it considers the probability that the drug never makes it through the clinical pathway to commercialization. GlobalData’s rNPV model uses proprietary likelihood of approval (LoA) and phase transition success rate (PTSR) data for the indication in the highest development stage, which can be found on GlobalData’s Pharmaceutical Intelligence Center.
