Zoetis has patented a method for detecting target analytes using nanostructure-binding partner conjugates. By mixing samples with specific detection conjugates and measuring changes in optical signals, the presence of analytes can be identified. The method involves utilizing metallic nanostructures and various additives for accurate detection. GlobalData’s report on Zoetis gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on Zoetis, Personalized cancer vaccines was a key innovation area identified from patents. Zoetis's grant share as of May 2024 was 49%. Grant share is based on the ratio of number of grants to total number of patents.
Detection of target analyte using nanostructure-binding partner conjugates
A recently granted patent (Publication Number: US11977072B2) discloses a method for detecting a target analyte in a sample using nanostructures coupled to binding partners. The method involves mixing the sample with specific detection conjugates, a blocking agent, polymeric materials, viscosity enhancers, salts, and a chelator in a solution. The nanostructures have an average tip to tip diameter ranging from 50 nm to 120 nm and are exposed to light within the ultraviolet-visible-infrared spectrum. By measuring the optical signal from the complex formed between the detection conjugates and the analyte, the presence of the target analyte in the sample can be determined based on changes in the optical signal compared to a baseline signal.
Furthermore, the patent details various parameters and components involved in the method, such as the specific concentrations of polymeric materials, viscosity enhancers, blocking agents, salts, and chelators. The method allows for the detection of nanogram, picogram, or femtogram quantities of the target analyte and can be performed in various settings like spectrophotometric cuvettes, microwell plates, or clinical analyzers. The nanostructures utilized in the method are specified to be gold metallic nanostructures, and the binding partners can include antibodies, antigens, receptors, and other biological macromolecules. The target analyte can range from proteins, enzymes, and nucleic acids to pathogenic antigens like viral, bacterial, fungal, or parasitic antigens, enabling a broad application scope for the detection method.
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