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Off-the-shelf CAR-T therapy: broadening the reach of precision medicine

Although it seems like a contradiction in terms, creating off-the-shelf versions of precision medicines, such as CAR-T therapies, is increasingly being seen as an answer to manufacturing challenges facing the current autologous approaches. Allie Nawrat explores Celyad’s allogeneic, off-the-shelf CAR-T therapy CYAD-101 as a case study of the model’s promise.


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