GE Healthcare’s Life Sciences business and integrated vaccine biotech company Valneva SE have successfully collaborated to optimise virus productivity in Valneva’s EB66 cell-line, a proprietary technology for the production of a wide variety of vaccines, including human and animal health.

Viral production in EB66 cells includes secreted viruses, such as measles, alphaviruses, influenza A and B strains, and intracellular viruses, such as the modified vaccinia Ankara (MVA) virus.

Go deeper with GlobalData

Premium Insights

The gold standard of business intelligence.

Find out more

Related Company Profiles

View all

This collaboration has led to the creation of a commercial cell culture medium, HyClone CDM4Avian, developed to address the challenges of media variability.

The new medium supports efficient and predictable virus production for manufacturers utilising EB66 cells, helping to  increase production reliability and boost end-product quality.

"The advent of cell-based production is helping manufacturers meet the growing need for vaccines to address global healthcare challenges."

Feasible for use throughout the entire cell-growth process, CDM4Avian is chemically defined and free from animal-derived components, which enhances product consistency and simplifies the regulatory processes for new products developed in EB66 cells.

See Also:

GE Healthcare Life Sciences upstream and cell culture general manager Morgan Norris said: “Working in close collaboration with Valneva and capturing their expertise in vaccine production has enabled us to successfully enhance productivity and create a novel cell culture medium for a vaccine industry undergoing a period of exciting change.

How well do you really know your competitors?

Access the most comprehensive Company Profiles on the market, powered by GlobalData. Save hours of research. Gain competitive edge.

Company Profile – free sample

Thank you!

Your download email will arrive shortly

Not ready to buy yet? Download a free sample

We are confident about the unique quality of our Company Profiles. However, we want you to make the most beneficial decision for your business, so we offer a free sample that you can download by submitting the below form

By GlobalData
Visit our Privacy Policy for more information about our services, how we may use, process and share your personal data, including information of your rights in respect of your personal data and how you can unsubscribe from future marketing communications. Our services are intended for corporate subscribers and you warrant that the email address submitted is your corporate email address.

"The advent of cell-based production is helping manufacturers meet the growing need for vaccines to address global healthcare challenges.”

Valneva president and chief executive officer Thomas Lingelbach and deputy chief executive officer Franck Grimaud said: “This collaboration with GE has been very successful and we are extremely pleased that our EB66 licensees now have access to a medium that will greatly ease the development of their new products.

"Coupled with the recent European Medicine Agency’s (EMA) decision to allow the production of live attenuated vaccines in cell-lines such as EB66, this strongly supports the choice of EB66 as a modern cell technology platform for vaccine development and manufacturing.”

Until now, only inactivated vaccines could be developed in EB66 cells within Europe.

The EMA recently decided to issue new guidelines on vaccine production in immortal cell lines allowing Valneva’s partners to now utilise the EB66 cell line to develop and manufacture live-attenuated vaccines (LAV), including Modified Vaccinia Ankara (MVA)-based vaccines, measles and oncolytic vaccines.