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February 27, 2020updated 01 Jun 2021 10:19am

Novavax starts animal testing of coronavirus vaccine candidates

US-based biotechnology company Novavax has begun testing its new coronavirus vaccine candidates in animal models. The company constructed several vaccine candidates against Covid-19.

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US-based biotechnology company Novavax has begun testing its new coronavirus vaccine candidates in animal models. The company constructed several vaccine candidates against Covid-19.

The company expects that findings from the preclinical testing will help determine an optimal candidate for human studies, with a clinical trial anticipated to begin in May or June.

Novavax’s candidates are based on its recombinant protein nanoparticle technology platform to produce antigens obtained from the coronavirus spike (S) protein.

To boost immune responses, the company plans to leverage its Matrix-M adjuvant with the vaccine candidate.

Novavax president and CEO Stanley Erck said: “Our previous experience working with other coronaviruses, including both MERS and SARS, allowed us to mobilise quickly against COVID-19 and successfully complete the critical preliminary steps to engineer viable vaccine candidates.

“Now that the protein has been expressed stably in our baculovirus system, we aim to identify the optimal candidate and scale up production of sufficient vaccine for preliminary clinical trials.”

Last month, the company announced plans to use its recombinant nanoparticle technology to develop a Covid-19 vaccine candidate.

Novavax previously developed MERS and SARS vaccines, said to have shown encouraging immunogenicity and complete protection in preclinical testing.

Furthermore, the company created a clinically immunogenetic Ebola vaccine candidate, which demonstrated effectiveness in primate studies.


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COVID-19 continues to dominate headlines the world over. It has already affected our lives forever. The way we work, shop, eat, seek medical advice, and socialize will all be different in the future. Quite how different remains to be seen, but all industries must plan for multiple eventualities.  Faced with an explosion of conflicting information on how to plan and implement successful recovery strategies, decision-makers are in dire need of a single, reliable source of intelligence.   GlobalData’s COVID-19 Executive Briefing gives you access to unparalleled data and insights to successfully navigate the uncertain road to recovery across the world’s largest industries. Understand every aspect of this disruptive theme by delving into: 
  •  COVID-19 infection update, with statistics on the spread, testing by country, as well as the latest data on vaccines and therapeutic developments 
  • Economic impact overview, covering stock market indices, GDP, unemployment rates, policy responses & GlobalData’s economic recovery scorecards 
  • Sector developments, with access to sector insight summaries, cross-sector indices and the leaders and laggards in each industry vertical 
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