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March 18, 2020

Regeneron identifies several antibodies against Covid-19

Regeneron Pharmaceuticals has announced the identification of hundreds of fully human antibodies against Covid-19, which is caused by the novel coronavirus.

Visit our Covid-19 microsite for the latest coronavirus news, analysis and updates

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by GlobalData
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Regeneron Pharmaceuticals has announced the identification of hundreds of fully human antibodies against Covid-19, caused by the novel coronavirus.

The virus-neutralising antibodies came from Regeneron’s genetically-modified VelocImmune mice, which have an immune system similar to humans.

Furthermore, the company isolated antibodies from recovered Covid-19 patients.

Regeneron plans to choose the top two antibodies to create a ‘cocktail’ therapy given as prophylaxis or a treatment for infected people.

Meanwhile, the company is using its VelociMab technology to formulate manufacturing-ready cell lines to enable immediate clinical-scale production of selected antibodies.

The aim is to generate several thousands of prophylactic doses per month by later this year. Regeneron also intends to produce smaller quantities for initial clinical testing in June or August.

Furthermore, the company partnered with the US Health & Human Services’ Biomedical Advanced Research and Defense Authority (BARDA) to boost capacity.

Regeneron Pharmaceuticals co-founder, president and chief scientific officer George Yancopoulos said: “Our three decades of investment in our VelociSuite antibody technologies, which accelerate and improve the traditional drug discovery process, have hopefully prepared us for this critical time and to meet this important challenge.

“Given the tremendous interest and concern around the Covid-19 pandemic, we will be providing regular and transparent updates on our discovery and development programmes.”

The company’s antibodies should act on the spike protein required by the virus to infect host cells.

Separately, Regeneron and Sanofi initiated a clinical programme of rheumatoid arthritis drug Kevzara (sarilumab) to treat hospitalised patients with severe Covid-19.

Related Companies

Free Whitepaper
img

What is the impact of China’s Zero-COVID lockdowns on economic activity, consumer goods and the foodservice industry?

While wanting to protect the country from being overwhelmed by Omicron, China’s adherence to a Zero-COVID policy is resulting in a significant economic downturn. COVID outbreaks in Shanghai, Beijing and many other Chinese cities will impact 2022’s economic growth as consumers and businesses experience rolling lockdowns, leading to a slowdown in domestic and international supply chains. China’s Zero-COVID policy is having a demonstrable impact on consumer-facing industries. Access GlobalData’s new whitepaper, China in 2022: the impact of China’s Zero-COVID lockdowns on economic activity, consumer goods and the foodservice industry, to examine the current situation in Shanghai and other cities in China, to better understand the worst-affected industry sectors, foodservice in particular, and to explore potential growth opportunities as China recovers. The white paper covers:
  • Which multinational companies have been affected?
  • What is the effect of lockdowns on foodservice?
  • What is the effect of lockdowns on Chinese ports?
  • Spotlight on Shanghai: what is the situation there?
  • How have Chinese consumers reacted?
  • How might the Chinese government react?
  • What are the potential growth opportunities?
by GlobalData
Enter your details here to receive your free Whitepaper.

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