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October 13, 2020

Rhizen signs oncology drug development deal with Curon

Swiss biopharma company Rhizen Pharmaceuticals has signed an exclusive licensing agreement with Curon Biopharmaceutical to develop and commercialise Tenalisib for oncology in the Greater China region.

Swiss biopharma company Rhizen Pharmaceuticals has signed an exclusive licensing agreement with Curon Biopharmaceutical to develop and commercialise Tenalisib for oncology in the Greater China region.

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Tenalisib, a highly selective dual PI3K delta and gamma inhibitor, is currently in Phase II clinical development for haematological malignancies.

The US Food and Drug Administration (FDA) granted fast track and orphan drug designations for the drug candidate Tenalisib as a treatment for relapsed / refractory peripheral T-cell lymphoma and cutaneous T-cell lymphoma (R / R PTCL and R / R CTCL).

Under the deal, Rhizen will receive an undisclosed upfront cash payment and is eligible for milestone payments.

The total deal value amounts to approximately $149.5m apart from royalties on annual net sales of Tenalisib.

Furthermore, Curon will gain exclusive development and commercialisation rights of Tenalisib for Greater China across all oncology indications.

Utilising its expertise in translational research, clinical development and regulatory registration and research partnership knowledge, the company will carry forward the clinical development in the area.

This will help fast-track the development and regulatory approval of Tenalisib in the territory.

Rhizen Pharmaceuticals president and CEO Swaroop Vakkalanka said: “We believe, Tenalisib’s outstanding safety could allow rational combinations with other approved/investigational agents and enable us to unlock the true potential of this class of drugs.”

Kun Tao from Yafo Capital acted as the financial advisor for Rhizen.

Curon president Zhihong Chen said: “Tenalisib has demonstrated great efficacy in lymphoma patients with outstanding safety profile, in-licensing this product to China would bring more effective and additional treatment options to Chinese cancer patients and greatly benefit these patients.”

In September, Rhizen published the results from Phase I / Ib trial of Tenalisib demonstrating good overall response rate in patients with relapsed / refractory T-cell lymphoma (TCL).

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img

2022: So far In Venture Capital

Global investment in 2022 has been majorly dominated by North America, Europe, and Asia Pacific, whereas the Middle East, and South and Central America have recorded low investments comparatively. In light of this, Europe and North America have been identified as the major destinations for Private Equity and Venture Capital (PE/VC) investments.   GlobalData’s whitepaper analyzes which sectors PE/VC firms have been investing in, looking at Technology, Media, and Telecom, with these sectors recording $356 billion and a deal volume of over 10,000 deals in 2022. Healthcare, Financial Services, Business & Consumer Services, and Construction sectors have also seen high investment activity by PE/VC firms, recording a deal value of over $70 billion each.   But what can this mean for you?   Understand how the Deals Database on GlobalData Explorer can be leveraged to:  
  • Track the Aggregate Investment Volumes in PE/VC-Stage firms across geographies and sectors, in addition to viewing the specific deals that drove these volumes
  • Identify the top investors already active in any sector-Geography combinations
  • Assess the Performance of Financial and Legal Advisors, supporting the Dealmaking in any segment of choice (Customizable League tables)
  • Understand what is driving the PE/VC fundraising (Deal Rationale)
  Consult our full report here and optimize your business strategy.
by GlobalData
Enter your details here to receive your free Report.

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