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Emisphere Technologies|23 February 2018

Eligen B12™

Eligen B12™ is a once-daily oral non-prescription medical food shown to normalise B12 levels without the need for an injection.

Eligen B12™ is a once-daily oral non-prescription medical food shown to normalise B12 levels without the need for an injection.

Eligen B12™ is indicated for the dietary management of patients who have a medically diagnosed vitamin B12 deficiency that is associated with a disease or condition that cannot be managed by a modification of the normal diet alone.

Eligen B12™ is the first product to market using Emisphere’s advanced Eligen® Technology, which utilises salcaprozate sodium (SNAC) to chaperone B12 through the gastric lining and directly into the bloodstream independent of intrinsic factor, a protein made in the stomach that normally facilitates B12 absorption.

This groundbreaking technology may have potential applications across a broad range of diseases and conditions. Most notably, Eligen® Technology is being used to develop oral formulations of insulin and GLP-1 receptor agonists.

The updated guidelines from the US Food and Drug Administration (FDA) state that medical foods, including Eligen B12™, no longer require a prescription. Now, it can be conveniently purchased at eligenb12.com and shipped to patients’ homes.

Emisphere's Eligen® Technology binds a delivery agent with a therapeutic compound without alternation. This process occurs when both agent and compound are in close proximity.
Originally published by Elsevier Journals on 24 May 2011, this white paper outlines an open-label, randomised, single-dose, parallel-group study of the pharmacokinetics of oral cyanocobalamin...
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