Age-related macular degeneration (AMD) is a progressive eye disease that affects the retina, the area of the eye responsible for central vision and sharpness. AMD is the most common cause of irreversible vision loss among the elderly, specifically those ages 50 years and older.

In the nine major pharmaceutical markets (9MM: US, France, Germany, Italy, Spain, UK, Japan, Australia, and China), GlobalData epidemiologists found that less than half of AMD cases were diagnosed in 2019, with Japan and China experiencing the most undiagnosed cases due to the large number of AMD cases in these markets.