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Symyx provides a faster, more reliable route to clinical trials by delivering drug products manufactured with a highly optimized and robust formulation. We have over a decade of experience working with the smallest biotechnology start-ups and the largest pharmaceutical companies. Symyx combines unsurpassed formulation expertise, high-productivity research technology and CGMP manufacturing capability in a single facility. Biopharmaceutical product developmentSymyx uses its expertise in formulation science, high-productivity research and biopharmaceutical product development to solve complex formulation problems ranging from proteins to peptides to antibodies. We develop highly optimized and robust formulations, so that clinical trials test the efficacy of the drug, not the limitations of the formulation. Pharmaceutical development using parallel experimentation technologySymyx utilizes microscale, parallel experimentation technology to quickly deliver information on our clients’ small-molecule candidates. Symyx scientists deliver critical solubility and solid-form selection information using microgram amounts of API, investigate a broad range of conditions for comprehensive accelerated stress testing and compatibility studies, and rapidly identify key process parameters for route selection and process optimization using array-based studies. CGMP fill and finish manufacturingSymyx integrates formulation development and CGMP fill and finish to enable direct transfer of liquid and lyophilized processes to early clinical manufacturing. We offer both manual and automated aseptic fills in a sterile environment that meets US and EU standards. Our facility provides in-process, release and stability testing services with a range of CGMP analytical techniques. Biological and chemical process developmentSymyx can help you quickly identify and optimize key process conditions and parameters to speed and ensure successful development. Biological:
Chemical:
Liquid, solid and lyophilized formulation studiesOptimize liquid, solid and lyophilized formulations for improved delivery, and investigate the effect of excipients on drug substance and other parameters. Biological:
Chemical:
Preformulation molecular studiesInvestigate the physical and biological properties of a molecule, identify key stresses and degradation products, create stability-indicating assays and select the feasible formulation for early clinical trials. Biological:
Chemical:
Clinical GMP fill and finish manufacturingDeliver liquid and lyophilized drug product in quantities suitable for preclinical and early clinical supply.
Symyx Technologies, Inc.
820 Calle Plano Camarillo CA 93012 USA Tel: +1 805 445 8422 Fax: +1 805 445 8428 Email: biopharm.info@symyx.com URL: www.symyx.com/cdmo |
![]() Process development: quickly identify and optimize key process conditions and parameters to speed and ensure successful development. ![]() Formulation studies: optimize liquid, solid and lyophilized formulations for improved delivery, and investigate the effect of excipients on drug substance and other parameters. |