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  1. OPTIMA Pharma
18 June 2018

New administration forms for pharmaceutical agents becoming increasingly important

The packaging industry has the responsibility to follow this trend and to develop new designs and present solutions. The idea behind COMEDCO is to make it easy and safe for pharmaceutical companies to start their new developments in transdermal and ODF products.

The COMEDCO portfolio includes laboratory or development equipment platforms, which are scalable to medium and large size production capacities.

Development expenses occur during the launch of ODF or TDS product. Here the machine builder can help to reach the objective faster and with less expenditure. Answers to questions such as ‘What is the best suitable application and dosing system for a certain drug?’, ‘What is the best carrier material for which drug?’, and ‘How can a correct homogeneous substance per piece or unit be guaranteed and controlled?’ can now be answered.

The production of transdermal dressings and ODF products starts with the coating process where the substance is applied to the carrier material by a COMEDCO machine. Depending on the product, a certain drying time has to be considered, which takes place within the machine.

Subsequently, the carrier material with the applied substance is cut and rolled into individual rolls. The product, depending on the drying process and the strict separation of different pharmaceutical substances, may require a batch process to avoid cross-contamination. The coating process takes place in the first part of the COMEDCO machine.

OPTIMA Pharma’s COMEDCO partner Coatema Coating Machinery provides a decade-long expertise in the development and distribution of different coating machinery. Projects from the medical and pharmaceutical industry are a part of its expertise. The company is well known worldwide for its diverse technology centre in coating technologies.

With COMEDCO, customers are able to rely on experts to define the different possibilities and discuss advantages and disadvantage of the different technologies for their product. In addition, OPTIMA Pharma’s coating experts are in close contact with scientific institutes and are well connected through several scientific projects.

Expert duo

The packaging process is completed in the second part of the COMEDCO machine. In this part of the machine, existing (product depending) carrier material can be removed, new carrier material introduced, and the film would be cut to a defined size, separated, reunited on a carrier film and packaged. The packaging of transdermal dressing is often more complex than packaging oral dispersible film due to a wider variety of product options and different processing methods. The COMEDCO machine offers continuous or intermittent converting and packaging processes.

This part of the COMEDCO machine is based on technologies from Optima Life Science. Optima Life Science offers expertise from a variety of completed projects for ODF and TDS products, as well as from state-of-the-art wound care packaging processes. The company made a name for itself across the industry through flexibility with complex automated processes, first with the production and packaging of diagnostic products and thereafter, in medical web converting.

Optima Life Science is part of the Optima Packaging Group, which has successfully built manufacturing and packaging machinery for decades, among other industries, also for the pharmaceutical industry and life science companies.

Loose connection or strong partnership?

An intense search for the right partner preceded the COMEDCO alliance. One of the deciding factors for the alliance was the perfectly complementary expertise of Coatema Coating Machinery GmbH and Optima Life Science. Both companies are similar regarding their focus. In addition, both companies are convinced that the partnership will bring many advantages to customers and end-users.

The contractual partner for customers will always be Optima Life Science, therefore, customers will benefit from one responsible party and a clear structure. Both companies provide expert contacts. In addition, both companies are still operating as separate entities if the project is related to only coating or packaging.

COMEDCO made its first public appearance during the Achema show. This joint kick-off emphasises the commitment to the alliance. A COMEDCO website is also available ( At the start of 2018, the founding of COMEDCO was contractually finalised. An initial joint order was won shortly after.

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