Through its Anhydro and e&e brands, SPX offers a range of drying technologies that meet the needs of wide ranging applications and industries.
Anhydro is a leading global brand within SPX’s Flow Technology Segment offering liquid concentration and powder processing solutions, as well as equipment for the international dairy, food, beverage, alcohol, pharmaceutical and chemical industries.
SPX designs, manufactures, installs and services a wide range of advanced Anhydro evaporation and drying equipment and solutions for customers in major industries around the world.
SPX Corporation (NYSE: SPW) is a Fortune 500 manufacturing leader that provides its customers with highly-specialised, engineered solutions to solve critical business issues. With headquarters in Charlotte, North Carolina, SPX has 15,000 employees in more than 35 countries worldwide.
Pharmaceutical spray drying
With thousands of Anhydro spray drying plants installed worldwide, SPX offers a comprehensive range of solutions for pharmaceutical spray drying applications:
- From basic GMP designs to aseptic processing
- Compact processing of more drug product than with other processing technologies
- Dedicated customisation based on world-leading experience and expertise
- Multiple processes, including API processing, spray encapsulation, spray agglomeration and spray cooling
- Comprehensive range of applications
- Scalable design space
- Complete control over particle size distribution
- Consistent accuracy and performance
- Maximum uptime with straightforward cleaning and maintenance
- Drying gas rate capacities from 35kg/hr and up
Anhydro spray drying solutions for the pharmaceutical industry feature FDA 21 CFR Part 11-compliant process control and data acquisition to accommodate individual customer requirements. SPX supplies the necessary process control and data acquisition solutions to facilitate successful validation.
SPX performs verification and provides complete documented quality control according to the GAMP V model.
Continuous and batch fluid bed / drying systems
SPX offers a complete range of Anhydro continuous and batch fluid beds for drying, cooling, granulation, agglomeration and classifying. Fluid beds can be used for processing of most types of powdered products. Anhydro fluid bed processes include drying, agglomeration, spray coating, cooling, dedusting and lecithination. Anhydro offers batch and continuous fluid beds, as well as fluid beds to be integrated into multi-stage spray drying plants.
Customised industrial drying systems
Anhydro industrial drying systems can be combined and customised for specific product applications. SPX provides experience, expertise, service and support covering all aspects of technology implementation, including feasibility studies and extensive test facilities.
All Anhydro brand dryers are designed, engineered and customised to provide unbeatable performance at the lowest possible cost. The majority of drying options can be supplied in standard and GMP configurations, while specialised options can be supplied in accordance with aseptic standards. Anhydro dryers range from small-scale plants with capacities of a few kilograms per hour to large-scale industrial plants.
Various evaporation techniques are used to concentrate fluids in wide ranging industries including dairy, food, pharmaceutical and chemical. The reason for evaporation or distillation may be to concentrate a product, such as milk for example.
There are a number of major safety issues to be addressed in modern spray drying plants and each plant needs to be specifically designed for its particular purpose and conditions.
Anhydro has just completed a high-profile project covering a 'proof of concept' scale 'sterilisation in place' aseptic spray dryer for aseptic processing of TB vaccines - the first in the world.
In order to meet the increased demand for Vitamin C for food and pharmaceutical applications, Zhengzhou Tuoyang Industry Company, a major producer of Vitamin C in China, has recently put a new production line in operation.
Anhydro has launched an advanced pharmaceutical spray dryer for aseptic and high containment processing. The spray dryer, MicraSpray (MS) 35, has now been further developed, conforming to regulatory requirements for truly aseptic production of sterile pyrogen-free powders. Applications include pr