Codexis has been granted a patent for engineered galactose oxidase enzymes, polypeptides, and polynucleotides, along with methods for their production. The invention is aimed at producing pharmaceutical and other compounds efficiently. GlobalData’s report on Codexis gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on Codexis, Bioethanol production GMOs was a key innovation area identified from patents. Codexis's grant share as of May 2024 was 27%. Grant share is based on the ratio of number of grants to total number of patents.
A recently granted patent (Publication Number: US12012618B2) discloses an engineered galactose oxidase with specific polypeptide sequences and substitutions, resulting in enhanced production of 2-ethynylglyceraldehyde with increased enantiomeric excess of the R-stereoisomer compared to the wild-type F. graminearium galactose oxidase. The engineered galactose oxidase includes substitutions at key positions in the polypeptide sequence, such as 291, 375, 453, and 465, leading to improved enzymatic activity.
Moreover, the patent covers variants of the engineered galactose oxidase with specific sequence identities to SEQ ID NOS: 1598, 1866, 1912, 2080, 2300, and/or 2424. These variants exhibit similar substitutions at various amino acid positions, enhancing the catalytic properties of the enzyme. The patent also includes claims for purified engineered galactose oxidase and compositions containing this modified enzyme, highlighting its potential applications in biocatalysis and industrial processes requiring selective oxidation reactions.
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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies
