Geron has been granted a patent for crystalline solids of 3-palmitoyl-amido-1,2-propanediol and 3-palmitoyl-amido-2-hydroxy-1-dimethoxytriphenylmethylether-propane, along with methods for their preparation and conversion from one form to another. GlobalData’s report on Geron gives a 360-degree view of the company including its patenting strategy. Buy the report here.
According to GlobalData’s company profile on Geron, Peptide pharmacophores was a key innovation area identified from patents. Geron's grant share as of June 2024 was 50%. Grant share is based on the ratio of number of grants to total number of patents.
Crystalline solids of specific palmitoyl-amido compounds
The granted patent US11987540B2 describes a crystalline solid of a specific compound identified by Formula I. The claims detail the physical properties of this crystalline solid, emphasizing its thermal characteristics as determined by differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA). Notably, the crystalline solid exhibits a first endotherm at 79.3°C and a second endotherm at approximately 102.5°C, indicating distinct thermal transitions that can be measured using DSC techniques.
Further elaborating on the thermal stability of the crystalline solid, the patent claims that TGA analysis reveals a single weight loss step commencing at around 200.5°C. This suggests a specific thermal behavior that may be relevant for applications requiring stability at elevated temperatures. Additionally, the second endotherm identified in the DSC analysis is characterized as a single peak endotherm, providing further insight into the thermal properties of the compound. These detailed claims contribute to the understanding of the crystalline solid's behavior under thermal conditions, which may have implications for its use in various industrial or pharmaceutical applications.
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