Global Blood Therapeutics has been granted a patent for a crystalline form of Compound I, a potential therapeutic compound. The patent covers the preparation, characterization, and use of this form of Compound I. GlobalData’s report on Global Blood Therapeutics gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on Global Blood Therapeutics, was a key innovation area identified from patents.

Crystalline form of compound i for medical use

Source: United States Patent and Trademark Office (USPTO). Credit: Global Blood Therapeutics Inc

The granted patent (Publication Number: US11851424B2) discloses a crystalline Compound I Form I with specific characteristics, including a unique X-ray powder diffractogram and a differential scanning calorimetry (DSC) curve showing an endotherm at about 111°C. The compound also has defined unit cell parameters, making it distinguishable and identifiable.

Additionally, the patent covers other crystalline forms of Compound I, such as Material II and HCl Form A, each with their own distinct X-ray powder diffractogram and DSC curve characteristics. The patent further extends to pharmaceutical compositions containing the crystalline Compound I Form I, either alone or in combination with other therapeutic agents, for treating disorders mediated by hemoglobin, particularly sickle cell disease. Methods for increasing oxygen affinity of hemoglobin S and treating sickle cell disease by administering the crystalline Compound I Form I are also claimed in the patent, highlighting its potential therapeutic applications in addressing hemoglobin-related disorders.

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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies