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Dermal Drug Testing: Pharmacokinetic, Pharmacodynamic and Bioequivalence Studies in the Dermis

We investigate the transport and effects of APIs/drugs in the dermis after local, topical or systemical application in the dermis – in-vivo and ex-vivo. We perform tissue-specific preclinical and clinical pharmacokinetic (PK) and pharmacodynamic (PD) studies of APIs/drugs as well as mechanistic studies of diseases. We can also investigate bioavailability/bioequivalence and perform metabolomics studies in-vivo and ex-vivo. For these investigations, we use microdialysis and our patented technique – open flow microperfusion (OFM).

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