Brain cancer is a very severe and highly debilitating disease that has become the subject of a great deal of research (Wrensch et al., 2002). Although it is not as common as other cancer types, and some forms of brain cancer are considered rare, the disease has been well-documented and discussed over the past decade (RARECARE, 2015). Glioblastoma is the most common and most aggressive form of brain cancer.

The ideal treatment for patients diagnosed with glioblastoma is surgery to remove as much of the tumor as possible, followed by chemotherapy and radiotherapy. Unfortunately glioblastomas are aggressive tumors and often appear resistant to treatment. The thin tendrils of glioblastoma that spread out into other parts of the brain make complete removal of the tumor difficult.

Research is ongoing to find the answers to tumor evolution in glioblastoma. Investigation into the functioning of genes and treatment are important areas of study, as the number of diagnosed incident cases of brain cancer and glioblastoma are projected to increase.

GlobalData projects that the number of diagnosed incident cases of brain cancer (including glioblastoma) in the seven major markets (7MM: US, France, Germany, Italy, Spain, UK, and Japan) is expected to increase from 55,084 diagnosed incident cases in 2014 to 62,226 diagnosed incident cases in 2024 at an annual growth rate (AGR) of 1.3%. Approximately 48% of all diagnosed incident cases of brain cancer in the 7MM take the form of glioblastoma. The number of diagnosed incident cases of glioblastoma in the seven major markets is expected to increase from 26,234 in 2014 to 29,606 diagnosed incident cases in 2024 (Figure 1).

Scientists at the University of Cambridge have announced the start of a new investigation that will look into the Zika virus’ ability to cross the blood brain barrier and target stem cells in the hopes that the virus can be harnessed to treat glioblastoma.

The cancer cells in glioblastoma resemble the stem cells in a developing brain, which could mean that Zika can be harnessed to treat glioblastoma. Details about the trend analysis and other discussions of brain cancer (including glioblastoma) epidemiology can be found in GlobalData’s EpiCast Report: Brain Cancer (including glioblastoma) – Epidemiology Forecast to 2024, and in GlobalData’s EpiCast Model: Brain Cancer (including glioblastoma) – Epidemiology Forecast to 2024.

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Figure 1: 7MM, Diagnosed Incident Cases of Glioblastoma, Men and Women, All Ages, 2014–2024, N.

Brain cancer

Source: GlobalData                                                                                                                                                  © GlobalData

5EU= France, Germany, Italy, Spain, UK; 7MM= US, 5EU, Japan