As part of a series of white papers tracking clinical trials activity across the world, GlobalData recently compiled a summary of the clinical trials initiated in 2016. The company captured records of 14,190 clinical trials across all diseases and phases that had a start date between 1 January and 31 December, 2016.
GlobalData analysed the dataset to identify the top 10 drugs investigated in industry-sponsored clinical trials in 2016. The top three drugs were nivolumab, pembrolizumab, and atezolizumab, with a total of 39, 37, and 24 clinical trials, respectively. These were followed by paclitaxel, cannabidiol, adalimumab biosimilar, secukinumab, bupivacaine, ipilimumab, and adalimumab.
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The majority of the trials initiated for these drugs were Phase III trials, closely followed by Phase II trials, as shown in Figure 1. Immuno-oncology drugs nivolumab and pembrolizumab topped the drugs used in industry-sponsored clinical trials in 2016. The overall dominance of monoclonal antibodies in clinical trials was clearly evident, with seven out of the top ten drugs being monoclonal antibodies.
