CPL

Contract Development and Manufacturing of Non-Sterile Liquid and Semi-Solid Products

CDMO of non-sterile liquid and semi-solid pharmaceutical products

CPL is a contract developer and manufacturer (CDMO) of non-sterile liquid and semi-solid pharmaceutical products.

The company is uniquely focused on the development, manufacturing, packaging, and testing of creams, ointments, gels, lotions, and non-sterile solutions, as well as suspensions and nasal sprays.

With a strong record of regulatory compliance, exceptional customer service, and product expertise, CPL is the trusted choice for your pharmaceutical outsourcing projects. By offering turnkey services, from development to commercial production, CPL creates strategic relationships with customers that result in long-term successes.

The company has been in business for more than 23 years and has grown to become one of the leading contract development and manufacture organisations (CDMO) for non-sterile liquid and semi-solid products for large, mid-size, and specialty branded and generic pharmaceutical customers in North America, Europe, and Asia Pacific.

Topical semi-solid and non-sterile liquid formulation and product development

CPL's team understands the unique challenges of developing liquid and semi-solid pharmaceutical products. Its product development services (PDS) team of 22 dedicated experts has a combined 90 years of formulation experience, with 75 years of analytical experience and has worked on a full spectrum of products.

The company's services include development of new formulations, process optimisation, analytical method development, clinical trial supplies manufacturing, and commercial scale-up. Its team has developed many new drug application (NDA), abbreviated new drug application (ANDA), 505(b)2, and over-the-counter (OTC) products within these dosage forms. CPL has state-of-the-art pre-formulation, formulation, and analytical testing equipment, as well as labs located in its manufacturing facility including a pilot manufacturing suite for scale-up and clinical trial material projects.

Commercial manufacturing and packaging services

CPL's good manufacturing practice (GMP) commercial operations are focused on the manufacturing and packaging of non-sterile liquid (suspensions, solutions, and nasal sprays) and semi-solid (gels, lotions, creams, and ointments) pharmaceutical products. A dedicated technology transfer team supports the company's customers with new product launches or the transfers of existing products into our commercial manufacturing operation.

CPL has a wide variety of mixing vessels and tanks, from 20kg pilot scale to 5,000kg commercial scale, which support a variety of product types, viscosities, and processes. Its packaging capabilities include metal and laminate tubes, plastic and glass bottles, as well as jars (including metered dose pumps), nasal spray devices, and foil sachets. CPL's offerings also include secondary packaging into unit cartons, labelling, and shrink-wrapping.

Analytical R&D, pharma product stability and testing services

As a full-service CDMO, CPL has a GMP analytical testing lab that supports product development and commercial manufacturing operations. Its GMP analytical lab provides research and development (R&D) services such as method development, cleaning validation, method transfers, and special studies.

The company conducts all routine product testing such as raw materials, bulk, and finished products, as well as microbiological testing in its internal micro lab. This lab is equipped with a large number of walk-in and portable stability chambers with ICH and custom conditions that are remotely monitored and connected to back-up generators.

Speciality pharmaceutical products manufacturing

Our manufacturing suite segregation and engineering controls allow for the handling and processing of many specialized products including high-alcohol containing or flammable materials, light or oxygen sensitivity, some potent compounds, corticosteroids and hormones. Our packaging lines support the filling of these products through use of nitrogen blanketing or dedicated areas for explosion-proof filling.

FDA and Health Canada registered facilities

CPL has two facilities, a manufacturing site in Mississauga and its testing lab in Markham, Ontario. Both sites are registered with the US Food and Drug Administration (FDA) and Health Canada and have been routinely audited by these agencies. CPL's facilities self-identify as generic manufacturing and testing sites under the US GDUFA law and are in current standing as such.

Contact Details

CPL (Contract Pharmaceuticals, Ltd)
7600 Danbro Crescent
Mississauga
L5N 6L6
Ontario
Canada
Contact: For new business inquiries in Eastern US and Canada, please contact David Tyler
Contact: Jan Sahai, Vice-President of Business Development
+1 905 821 7600 x 265
David Tyler: +1 716 683 3740
DTyler@cplltd.com
jsahai@cplltd.com
www.cplltd.com

Available White Papers

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Determination of Absorption of Isopropyl Myristate in Processing Equipment and Packaging Material by Liquid Extraction and Gas Chromatography 19 January 2017 Isopropyl myristate (IPM) is widely used as a penetration enhancer and emollient in topical formulations.

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Quantitative Determination of Multiple Ingredients in Topical Formulation by Gas Chromatography 07 January 2015 Gas chromatography (GC) is a typical chromatographic method used to separate and quantitatively determine analytes that can be volatised without decomposition.

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CPL: Product Development through Commercialisation 01 October 2014 CPL develops and manufactures non-sterile liquid and semi-solid pharmaceutical products. We are solely focused on these dosage forms and have built our reputation as an industry-leading contract development and manufacturing organisation (CDMO).