MEDELPHARM

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Tablet Press Manufacture for Compaction Simulation and Powder Analysis

MEDELPHARM is a high-precision engineering company manufacturing research and development (R&D) tablet presses and providing innovative solutions for powder analysis and formulation.

MEDELPHARM is a specialist in the development, design, and manufacture of research and development (R&D) tablet presses and compaction simulators for powder compaction.

This high-precision engineering company provides intelligent tablet press technology and software development solutions for powder analysis and formulation.

MEDELPHARM focuses on the continuous development of innovative research and development presses (hardware and software), compaction simulation of industrial production cycles, powder characteriation and formulation services, compression, and material science. As compressed powders can be found everywhere, the applications encompass the pharmaceutical, cosmetics, food and nutraceuticals, chemistry & detergents, batteries & catalysts and explosives & nuclear industries.

R&D press for tablet development

The STYL’One Nano is the revolutionary benchtop R&D tablet press for demanding formulation scientists with price performance in mind. From API/excipient characterization, analytical development to formulation feasibility assessment and optimization, develop your single-layer formulation with only a few grams of powder.

Multi tip tooling on STYL’One Nano Benchtop Press.
Mini tablets patient-friendly systems for paediatric and geriatric applications.
STYL’One Nano Benchtop press powder zone and smart gravity feed shoe.
STYL’One Evo and STYL’One Nano R&D Presses.
STYL'One Evo Full Containment OEB 5 GMP installation.
External lubrication puff box and micro dosing unit.
Calibrated manual lubrication spray.
STYL’One Evo Dry Granulation and Roll Compaction mimicking
STYL’One Nano R&D Benchtop Press | Easy change of tooling.

The STYL’One Evo versatile compaction simulator is a high-speed, all-in-one single and multilayer tool designed for use in tablet development from early formulation to scale-up at production speed.

The machine characterizes essential powder properties and active pharmaceutical ingredients (API). It tests their suitability by simulating industrial production cycles, typically up to 400,000 tab/hour (dwell time <2ml), with only a few grams of powder needed.

The STYL’One Evo is designed for ease-of-use, compact footprint, and offers easy exchange of B, D (EU │TSM), oversized or core rods tooling. An optional micro-dosing unit, tab-in-tab device, GMP module with weight regulation, and force feeding are just a few of the available accessories offered with production mind.

More than 250 MEDELPHARM STYL’One units have been installed worldwide.

Quality by Design (QbD) R&D tablet press

QbD is a concept to produce a drug in a repeatable and cost-effective way. The QbD concept is in the heart of the design and development of the STYL’One R&D tablet press.

Machine operator protection during tablet production

With a global trend of powders being more and more potent, MEDELPHARM makes no compromise on user protection during tableting offering multiple solutions from wash-in-place to full containment OEB 5.

Dry granulation formulation development

Deciding on the right granulation process to meet your needs can be very material consuming. With the STYL’One Evo roller compaction simulation tool, you can identify the feasibility and impact of dry granulation directly at lab-scale with a limited amount of powder.

Training courses for tablet formulation and production

MEDELPHARM offers a range of training courses that are recognised by French authorities. The company aims to offer its extensive knowledge through effective training.

MEDELPHARM also offers its professional tableting instruments to various universities for training purposes so students can gain experience on current and future working methods. The company has university partnerships worldwide.

Maintenance, FAT, and SAT

MEDELPHARM offers services such as URS definition, installation, FAT, SAT, training and support, maintenance, and calibration, as well as consumables and wear and tear parts.

Powder processing solutions

MEDELPHARM distributes for France and Belgium renowned and innovative technologies in powder processing from lab scale to production, in association with partners worldwide, primarily KORSCH AG with its internationally renowned range of rotary presses.

Other collaboration partners include:

  • LB Bohle: Leading supplier of special process machines for weighing, granulation, sieving, blending, and coating.
  • Caleva: Market leader in manufacturing and developing equipment for the production of pellets (beads or spheroids) by extrusion and spheronization™
  • Fitzpatrick: Leading manufacturer of pharmaceutical hammer mills
  • MG2: Acclaimed Capsule filling equipment specialist and packaging solution manufacturer.
  • Quadro:Renowned manufacturer inventor of conical mills for consistent size reduction and uniform tableting.
  • ProCepT:Specialist offering innovative solutions for drying, agglomeration, tablet coating and mixing applications.

MEDELPHARM Science Lab

MEDELPHARM’s tableting and powder characterisation laboratory houses a team of research scientists and a range of sophisticated instrumentation dedicated to supporting clients with their product development needs. These include material characterisation, scale-up, small batch production, formulation, troubleshooting.

Innovative measuring equipment include STYL’One Nano and Evo compaction simulators, Smart Test 50, a CALEVA mini coater, a Quadro SLS multifunctional scalable lab system and a Comil U5, as an Accupyc (Micromeritics) Helium Pycnometer to measure true density, a turbula mixer, a disintegration bath and a friability tester.

About MEDELPHARM

Headquartered near Lyon, MEDELPHARM is a high-precision engineering company manufacturing R&D tablet presses and providing innovative solutions for powder characterisation and formulation.

Since 1985, MEDELPHARM is a specialist in tableting instruments ‘Made by people for people’, that work with high-speed and precision but at the same time are very easy-to-use. With its historical background in actual production, MEDELPHARM has a deep understanding of the R&D requirements that apply to tableting processes.

For formulation and pilot plant scientists around the world looking for assistance in powder characterisation, solid dosage formulation or production troubleshooting, MEDELPHARM can offer a comprehensive portfolio of versatile R&D presses and high-speed compaction simulators supported by a team of dedicated scientists.

Since the end of 2022, it has been a member of the international KORSCH Group, enhancing its worldwide reach.

White Papers

Videos

  • STYL’One Nano | R&D Benchtop Tablet Press

    The STYL’One Nano is the revolutionary benchtop R&D tablet press for demanding formulation scientists. From API/excipient characterisation, analytical development to formulation feasibility assessment and optimisation, develop your single-layer formu

  • STYL’One Evo | Multilayer Tablet Development

    STYL’One Evo’s sophisticated design can handle complex tablet forms of up to five layers, incorporating three different powders thanks to the multi-layer module. Develop a robust multilayer formulation thanks to STYL’One Evo.

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