Medelpharm Tablet Press Manufacture for Compaction Simulation and Powder Analysis

Medelpharm is a specialist in the development, design, and manufacture of research and development (R&D) tablet presses for powder compression.

This high-precision engineering company provides intelligent tablet press technology and software development solutions for powder analysis and formulation

Medelpharm focuses on continuous development of innovative research presses (hardware and software), compaction simulation of industrial production cycles, powder characterisation and formulation services, compression, and material science in the pharmaceutical, food, and cosmetics markets.

R&D press for tablet development

The new STYL’One Evolution tableting instrument is a high-speed, all-in-one multilayer tool designed for use in tablet development from early formulation to scale-up at production speed.

The machine characterises essential powder properties and active pharmaceutical ingredients (API). It tests their suitability by simulating industrial production cycles, typically up to 400,000 tab/hour (dwell time <2ml), with only a few grams of powder needed.

Machine operator protection during tablet production

Making no compromises on user protection during tableting, from early research to multilayer production scale-up, Medelpharm follows a global trend. The company offers different levels of operator protection from wash-in-place to full containment OEL 5 for the most potent drug substances.

Dry granulation compaction for small scale development

Dry granulation with roll compaction hybrid modelling is a topic intensively pursued by Medelpharm in close cooperation with the University of Düsseldorf.

Quality by Design (QbD) R&D tablet press

QbD is a concept to produce a drug in a repeatable and cost-effective way. The QbD concept is in the heart of the design and develpment of the STYL’One R&D tablet press.

Powder compaction analysis software

The ANALIS data acquisition and control package automatically explores and analyses the design of formula with efficiency in investigating critical attributes.

Collected data is analysed and presented in a user-friendly tabular or graphical format.

Tablet compaction and powder analysis

The STYL’One Evolution is easy to use, with a compact, door-size design. It offers a clean and easy exchange of B, D (EU │TSM) oversized, core rods.

Valuable accessories are available such as the micro-dosing unit, a tab-in-tab device, a good manufacturing practice (GMP) module with weight regulation and force feeding, and a heated die.

STYLCAM / STYL’One has been installed more than 100 times worldwide and users are still enjoying ease of-use with no trade-off.

Training courses for tablet formulation and production

Medelpharm offers a range of training courses that are recognised by French authorities. The company aims to offer its extensive knowledge through effective training.

Medelpharm also offers its professional tableting instruments to various universities for training purposes so students can gain experience on current and future working methods. The company has university partnerships worldwide.

Maintenance, FAT, and SAT

Medelpharm offers services such as URS definition, installation, FAT, SAT, training and support, maintenance, and calibration, as well as consumables and wear and tear parts.

Powder processing solutions

Medelpharm distributes renowned and innovative technologies in powder processing from lab-scale to production with brands such as supplier of special process machines LB Bohle, manufacturer and developer of equipment for the production of pellets Caleva, and manufacturer of pharmaceutical hammer mills Fitzpatrick.

Conical mill for particle size reduction and uniform tableting

Quadro designs and manufactures leading technology for uniform size reduction, sieving, deagglomaration and dispersion.

Procept offers a comprehensive range of lab scale R&D particle processing equipment for drying, agglomeration, coating and mixing applications.

Laboratory services

In mid-2017, Medelpharm decided to leave its laboratory in the heart of the University of Lyon and built a laboratory on its own premises. This laboratory has a controlled atmosphere so it can perform powder characterisation and analysis.

It also houses innovative measuring equipment such as the STYL’One Tableting Instrument, Smart Test 50, a CALEVA mini coater, a Quadro SLS multifunctional scalable lab system and a Comil U5, as well as an Accupyc (Micromeritics) Helium Pycnometer to measure true density, a turbula mixer, a disintegration bath and a friability tester.

About Medelpharm

Medelpharm is headquartered in Lyon, South-East France. Its team of experienced scientists provide powder characterisation services for screening of numerous formulations and testing powder flowability, powder densities, and tabletability.

Distribution of the STYL’One Tableting instrument is part of a global partnership with the Romaco Group.

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Press Release

Medelpharm to Attend Making Pharmaceuticals

Medelpharm has announced that it will be showcasing at the Making Pharmaceuticals in Coventry, UK. 

Product and Services
White Papers

Using Multi-Layer Tab-in-Tab or Tablets for Extended Release Formulations

Many options exist depending on the nature of the active pharmaceutical ingredient (API) and the required release profile properties, including hydrophilic or lipophilic matrices, osmotic pumps, coated tablets or pellets with pH-sensitive polymers.


12, rue des petites Combes,

Z.I. Nord

F-01700 Beynost


+33 478 976 210 +33 478 88 18 65 Company Video: External lubrication on STYL'One Evolution

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Press Release

24 April 2019

Medelpharm has announced that it will be showcasing at the Making Pharmaceuticals in Coventry, UK. 

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22 November 2018

Medelpharm has announced a forthcoming product launch of the STYL’One Nano at the ALL4PACK exhibition in Paris, France.

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14 November 2018

Medelpharm has unveiled a new generation of research and development (R&D) press with the STYL’One Nano.

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25 October 2018

Medelpharm is pleased to announce its attendance of the AAPS PharmSci 360 conference. 

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1 October 2018

MEDELPHARM's strategic marketing director Regis Cazes (MS, MBA) has been invited to speak at the 'Tablet & Capsules Hands-On Short Course' hosted by the University of Maryland School of Pharmacy.

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27 August 2018

Medelpharm is pleased to announce its attendance at CPhl Worldwide - IFEMA, the Trade Fair Institution of Madrid.

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20 August 2018

Medelpharm has announced a hands-on session about compaction simulation, compression profiles and how to solve capping issues through pre-compression, compression speed and producing bi-layer tablets and tab-in-tab.

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3 July 2018

Medelpharm describes how it impressed visitors at the ACHEMA expo in Frankfurt with the presentation of the STYL’One Evolution Multilayer Compaction Simulator.

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29 May 2018

Medelpharm will be showcasing its latest research and development (R&D) tablet press machines and powder analysis and formulation solutions at the ACHEMA tradeshow in Frankfurt am Main, Germany.

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8 May 2018

Medelpharm will be exhibiting its latest research and development (R&D) tablet presses and solutions for powder analysis and formulation at the FCE Pharma Expo, Sao Paolo, Brazil.

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5 April 2018

Medelpharm has announced it will be showcasing its latest technologies at Korea Pack.

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30 November 2017

Hundreds of attendees found their way to the tool in the jungle of formulation at AAPS booth 2003: The STYL’One Tableting Instrument LIVE.

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9 October 2017

Medelpharm has announced it will be showcasing the renowned STYL'One Evolution tableting instrument with its latest innovative accessories at CPhI Frankfurt.

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12, rue des petites Combes,

Z.I. Nord

F-01700 Beynost


+33 478 976 210 +33 478 88 18 65 Company Video: External lubrication on STYL'One Evolution

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