
Natoli
Tablet Compression Tooling Solutions for Pharmaceutical Applications
Natoli supplies tablet compression tooling, tablet presses, and control system software for the pharmaceutical sector.

Saint Charles, MO 63304,
United States of America
Natoli Engineering is a global supplier of tablet compression tooling and a full-service provider of tablet presses, control system software, and premium replacement parts for tablet presses and encapsulation machines in the pharmaceutical sector.
We provide formulation development and analytical/testing services, unparalleled technical support and troubleshooting, technical training courses, and a comprehensive catalogue of tablet compression accessories.
Founded on a commitment to manufacturing and delivering high-quality products, we continue to build on half a century of innovation and industry leadership.
Comprehensive services for tablet compression
Natoli’s headquarters in St Charles, Missouri, includes administrative, manufacturing, refurbishing, training, a laboratory, and scientific research facilities.
Our service centres in Long Island, New York; Southern California; and Szczecin, Poland, offer regional customer support and supply parts, accessories, tooling refurbishing, maintenance, training, and other services.
In addition, Natoli Scientific’s laboratory facility in Telford, Pennsylvania, provides formulation evaluation, training, and contract research and consulting services.
The Natoli Institute for Industrial Pharmacy Research and Development at Long Island University carries out formulation assessments and research into new formulation techniques and technologies.
High-quality, precise compression solutions
Natoli’s products are precision-engineered to give our clients the results they need. When time is money, superior parts mean higher outputs for the companies that use our products.
We develop premium parts from premium materials, and our steel is regarded highly among our clients – we do not stock steel unless it meets the highest standards of quality. We are also the only tooling manufacturer with a metallurgist on staff.
On-demand supply of tablet compression components
Natoli stocks common wear parts from regional service centres worldwide, allowing us to ship them faster and reduce downtime for clients’ production lines. We aim to guarantee unrivalled delivery times with our tooling.
When our customers purchase tablet compression tooling, tablet presses, encapsulation parts, or accessories, they are investing in a long-term partnership with Natoli.
We not only provide the correct tools for our clients, but also the experience and knowledge to enable their success. We offer the full-service solutions and products customers need to be their best.
Full-service solutions and client support
Natoli has experts to support our customers at every stage of product development, from formulation to quality assurance.
Support services are available at our laboratory in Telford, Pennsylvania, to ensure product success through formulation, testing and production.
In addition, our hands-on training courses held throughout the year provide industry professionals from around the world with the opportunity to advance their knowledge and gain proficiency.
We offer tooling, tablet presses, accessories, encapsulation parts and more to help our clients succeed in the solid oral dose industry.
About Natoli
Founded in 1973 by Carmelo Natoli, Natoli offers tablet compression and encapsulation services to the pharmaceutical, nutraceutical, veterinary, confectionery, and cannabis industries.
We are a family-owned company with decades of experience in the tablet compression industry. Our top experts have been in the industry for as long as Natoli has existed, if not longer, and we aim to bring the same level of dedication to our customers and the products we develop.


Tablet Presses
We offer a diverse line of best-in-class tablet presses, from single-station R&D laboratory models to heavy-duty production rotary presses.

Tablet Press Replacement Parts
We maintain an extensive inventory of over 250,000 premium tablet press replacement parts and turrets for virtually all press types, with most available for same-day shipping.

Encapsulation Machine Change and Spare Parts
We manufacture premium change parts for the NCF-45 encapsulation machine. Parts for changing capsule size include dosing disks, capsule feeders, magazine assemblies, upper and lower segments, pins, and more.

Control System Software
With its easy-to-use operator interface with a variety of features, our proprietary Natoli AIM™ Data Acquisition and Analytical Software and operating system platform make tablet and capsule R&D and manufacturing systems faster and easier to work with.
Welcome to Natoli
Natoli supplies tablet compression tooling and tablet presses, control system software, and premium replacement parts for tablet presses and encapsulation machines in the pharmaceutical sector.
Know Your Options: Choices Among Punch Heads, Barrels, and Tips—as well as in Die Shapes and Materials—Can Help Fine-Tune Tableting
The basics of rotary tablet compression tooling have stood the test of time. However, the specifications of tooling design have become more sophisticated.
R&D Tableting & Tablet Profiling
Tablet manufacturing poses many challenges, but it is still the preferred dosage form in the pharmaceutical and dietary supplement industries. Tableting is also common in food, candy, confectionery, industrial industries, and even some military applications.
New Natoli Tablet Press and Tooling Training Scheduled
Sharpen your skills in tablet press setup, operation, and maintenance procedures
11 May 2022Natoli Headquarters
- 636.926.8900
- marketing@natoli.com
- natoli.com
Telephone Number
Email Address
Links
Natoli Technical Centre, Poland
- +48 693-975-705
Telephone Number
Natoli Technical Centre, Long Island
- (631) 655-0174
Telephone Number
Natoli Technical Centre, Southern California
- (657)208-5247
Telephone Number
Natoli Scientific
- (636) 926-8900
Telephone Number
Natoli Institute at Long Island University
Natoli at the Department of Pharmaceutics Faculty of Pharmacy University of Karachi
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