177Lu-PNT6555 is under clinical development by Eli Lilly and Co and currently in Phase I for Solid Tumor. According to GlobalData, Phase I drugs for Solid Tumor have a 70% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how 177Lu-PNT6555’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

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GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

177Lu-PNT6555 overview

177Lu-PNT6555 is under development for the treatment of solid tumor, metastatic colorectal cancer, metastatic adenocarcinoma of the pancreas, metastatic melanoma, head and neck cancer squamous cell carcinoma, gastroesophageal (ge) junction carcinomas, oral cavity (mouth) cancer, oropharyngeal cancer, hypopharyngeal cancer, nasopharyngeal cancer, laryngeal cancer
esophageal squamous cell carcinoma (ESCC), soft tissue sarcoma. It consists of radioligand conjugated to lutetium 177. The drug candidate is a D-ala-boroPro based FAP targeting radioligand. It is administered by intravenous route.

Eli Lilly and Co overview

Eli Lilly and Co (Lilly) is a healthcare company that discovers, develops, and markets human healthcare products. The company offers medicines for cardiovascular conditions, diabetes, endocrinology, cancer, neurological problems, autoimmune disorders, men’s health, and musculoskeletal problems. The company distributes its pharmaceutical health products through independent wholesale distributors. Lilly conducts research and development activities to discover and deliver innovative medicines. It promotes products through sales representatives and marketing agreements with other pharmaceutical companies. The company operates R&D facilities, and production and distribution facilities in North America, South America, Europe, the Middle East, Africa and Asia-Pacific. Lilly is headquartered in Indianapolis, Indiana, the US.

For a complete picture of 177Lu-PNT6555’s drug-specific PTSR and LoA scores, buy the report here.

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.