Crinecerfont is a small molecule commercialized by Neurocrine Biosciences, with a leading Pre-Registration program in Congenital Adrenal Hyperplasia (Adrenogenital Syndrome). According to Globaldata, it is involved in 6 clinical trials, which were completed. GlobalData uses proprietary data and analytics to provide a complete picture of Crinecerfonts valuation in its risk-adjusted NPV model (rNPV). Buy the model here.
The revenue for Crinecerfont is expected to reach an annual total of $662 mn by 2034 in the US based off GlobalDatas Expiry Model. The drugs revenue forecasts along with estimated costs are used to measure the value of an investment opportunity in that drug, otherwise known as net present value (NPV). Applying the drugs phase transition success rate to remaining R&D costs and likelihood of approval (LoA) to sales related costs provides a risk-adjusted NPV model (rNPV). The rNPV model is a more conservative valuation measure that accounts for the risk of a drug in clinical development failing to progress.
Crinecerfont Overview
Crinecerfont (NBI-74788) is under development for the treatment of congenital adrenal hyperplasia. The drug candidate target corticotropin-releasing factor receptor 1. It is administered through oral route in the form of capsule and solution.
Neurocrine Biosciences Overview
Neurocrine Biosciences (Neurocrine) is a biopharmaceutical company that discovers, develops, and markets neurological drugs. The companys lead product Ingrezza, is a vesicular monoamine transporter 2 (VMAT2) inhibitor to treat adults with tardive dyskinesia and chorea associated with Huntingtons disease. It is developing a pipeline of drug candidates for various indications in neurology, neuroendocrinology, and neuropsychiatry. Neurocrine also conducts clinical trials and studies for diseases such as movement disorders, epilepsy, and congenital adrenal hyperplasia, among others. The company works in collaboration with Mitsubishi Tanabe Pharma and AbbVie for products distribution. Neurocrine is headquartered in San Diego, California, the US.
The company reported revenues of (US Dollars) US$1,887.1 million for the fiscal year ended December 2023 (FY2023), an increase of 26.8% over FY2022. In FY2023, the companys operating margin was 13.3%, compared to an operating margin of 12% in FY2022. In FY2023, the company recorded a net margin of 13.2%, compared to a net margin of 10.4% in FY2022.
The company reported revenues of US$515.3 million for the first quarter ended March 2024, an increase of 0% over the previous quarter.
For a complete picture of Crinecerfonts valuation, buy the drugs risk-adjusted NPV model (rNPV) here.
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