Vorolanib is under clinical development by EyePoint Pharmaceuticals and currently in Phase II for Diabetic Macular Edema. According to GlobalData, Phase II drugs for Diabetic Macular Edema have a 46% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how Vorolanib’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
Vorolanib is under development for the treatment of wet age-related macular degeneration, nonproliferative diabetic retinopathy (NPDR) diabetic macular edema. The drug candidate is a combination of a bioerodible formulation of its proprietary Durasert sustained-release technology with vorolanib. It is administered through intravitreal route. The drug candidate acts by targeting VEGF. The therapeutic candidate is developed based on Durasert technology and delivered using Medidur to provide sustained release. Medidur is a miniaturized, injectable, sustained-release drug delivery system. It was also under development for the treatment of dry age-related macular degeneration and retinal vein occlusion.
EyePoint Pharmaceuticals overview
EyePoint Pharmaceuticals (EyePoint), formerly pSivida, is a pharmaceutical company that develops and commercializes therapies for treatment of eye disorders. The company utilizes its Duraset platform, a miniaturized, injectable, and sustained delivery system to develop its product. Its pipeline products includes EYP-1901, an investigational sustained delivery intravital anti-VEGF treatment that targets wet age-related macular degeneration (Wet AMD), non-proliferative diabetic retinopathy (NPDR), and diabetic macularedema (DME). The company also markets its product such as Yutiq, a fluocinolone acetonide intravitreal implant to treat chronic non-infectious uvetis; and Dexycu for treatment of postoperative inflammation. EyePoint is headquartered in Watertown, Massachusetts, the US.
For a complete picture of Vorolanib’s drug-specific PTSR and LoA scores, buy the report here.