Aptar Pharma Setting the Standard for Drug Delivery

Nasal spray technology, droppers, and pDMI

Aptar Pharma provides high-standard specialised products including nasal spray technology, preservative-free ophthalmic droppers, and pressurised metered dose inhaler (pDMI) metering systems.

For decades, the company has formed these innovative healthcare technologies to become a trusted partner of the healthcare industry.

Aptar Pharma is an expert in regulatory matters and it helps partners simplify and increase compliance. The company continuously offers high-quality and safe products for its customers’.

Spray pump technology for nasal and other applications

Aptar Pharma’s spray technologies can be used in the treatment of allergic rhinitis, cough and cold or dermal diseases, and pain management (including central nervous system). They are highly customisable for branding, and are suitable for a wide range of drug formulations, including gels and lotions. A variety of dose volumes and actuators allows individual solutions.

The Advanced Preservative Free pump is a premium device used for nasal multi-dose applications and is recognised for its high-quality. It features a unique tip seal and filter technology, which avoids any crystallisation and prevents air contamination. In addition, each device is tested for seal and ventilation integrity to ensure microbiological safety.

Latitude® is a side-actuated nasal spray device designed for easy self-administration for improved patient compliance. It has a safety cap covering the short, motionless nozzle and when applying, the patients’ fingers do not come into contact with the nostrils.

Multidose, preservative-free eyecare dispenser

In recent years, several studies have shown that the chronic use of preserved eyecare medication leads to significant, undesirable side effects. To support both patient adherence and effective treatment, Aptar Pharma has developed an entirely new Multidose system, which makes preservatives obsolete.

Using a market-proven tip-seal and filter technology, the system secures absolute microbiological safety by pure mechanical means only. No debatable additives are used.

Globally, more than 100 commercial references, including both prescription medications and consumer products, have shown that the system is widely accepted. A recent FDA approval of a leading eyecare drug using this technology proves the unrivalled microbiological safety.

Continuous dispensing without propellant

Aptar Pharma’s Bag on Valve system allows for hygienic and convenient dispensing of drug products. Its 360° use supports patient and consumer adherence and the technology itself ensures ultimate protection of various formulations.

Established on the market for years, Bag on Valve systems have been continuously improved by Aptar Pharma.

Metering valves for pressurised metered dose inhalers (pMDI)

Aptar Pharma provides a range of dose indicators and delivery methods for pMDIs, which are used in the treatment of asthma and COPD.

The DF30 metering valve platform is suitable for solution and suspension-based formulations. Aptar Pharma manufactures this robust design at three facilities across Europe and Asia, focusing on consistent and accurate performance. The device contains elastomeric seals, which are designed to maintain chemical integrity within pMDI container closure systems.

Aptar Pharma’s eDose Counter is a reliable aerosol metering valve for pMDIs. This intellectual property (IP) protected product has a large and legible display showing the user how many doses are remaining. This is designed to increase patient trust and compliance.

Included are reminders and end-of-life warnings, which are fully integrated in the actuator.

Premium elastomeric closure systems for injectables

Aptar Pharma is a trusted partner of leading pharmaceutical companies in the design and manufacturing of elastomeric closures for parenteral applications.

The company is a pioneer in ready-to-sterilise components and sterile stoppers such as needle shields, tip caps, plungers, lyophilisation stoppers, small and large vial stoppers, as well as pre-filled syringe components.
Driven by quality, service, and innovation, Aptar Pharma’s products meet evolving drug industry demands for cleanliness, efficiency, and compliance.

Regulatory support and drug master files (DMF)

Aptar Pharma offers a wide range of added-value services for full product support. Including laboratory and research support, the company answers any technical query and assists clients with regulatory submissions.
Aptar Pharma’s team are active members of Association Française de Normalisation (AFNOR), German Institute for Standardisation (DIN), and International Standards Organisation (ISO) committees, while also maintaining a range of drug master files (DMF) in the US and Canada.

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Press Release

Aptar Pharma Adds Nasal Pump Manufacturing Capacity in North America

Aptar Pharma added manufacturing capacity in North America for its Child-Resistant (CR) and Senior-Friendly (SF) Classic Nasal Pumps.

White Papers

Nasal Drug Delivery Devices and Pain Management Systems

Worth an estimated >2bn in 2009, the nasally administered systemic drugs market has an increasing generics sector, is placing greater emphasis on patient compliance and convenience, and is benefitting from an increasingly ageing population.

Address
Aptar Radolfzell GmbH

Oeschlestr. 54 – 56

78315 Radolfzell

Germany

+49 7732 801 0 +49 7732 801 226 www.aptar.com/pharma

Aptar Pharma Images

Products and Services

Press Release

14 June 2017

Aptar Pharma added manufacturing capacity in North America for its Child-Resistant (CR) and Senior-Friendly (SF) Classic Nasal Pumps.

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15 May 2017

Aptar Pharma has announced approval by the European Medicines Agency (EMA) for integrated electronic nasal lockout device e-Lockout following a multi-year development with Takeda Pharmaceuticals International.

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2 May 2017

Aptar Pharma has announced it is entering a partnership with Kali Care to develop a monitoring adherence solution for ophthalmic clinical trials.

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24 March 2017

Aptar Pharma has announced its multi-dose Ophthalmic Squeeze Dispenser has been selected for a dry eye prescription product in the US.

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22 March 2017

Aptar Pharma Congers' state-of-the-art manufacturing facility was inaugurated March 20th by AptarGroup's president and chief executive officer (CEO) Stephan Tanda, president of Aptar Pharma Salim Haffar, and president of Aptar Pharma North America Alex Theodorakis. Several Aptar Pharma customers in North America were also invited.

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10 January 2017

The Respiratory Drug Delivery (RDD®) Europe scientific conference will welcome pulmonary and nasal drug delivery experts from around the world to Antibes, France.

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14 June 2009

Pfeiffer Cartridge Pump Systems (CPS) represent a new generation of dispensing systems for both preserved and unpreserved solutions. The cartridge family offers a nasal spray pump, as well as pumps for topical, oral and aural application. The CPS are a direct response to incr

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Regional Offices

Aptar Radolfzell GmbH

Oeschlestr. 54 – 56

78315 Radolfzell

Germany

+49 7732 801 0 +49 7732 801 226 www.aptar.com/pharma
Aptar Louveciennes Sales Office

Aptar Pharma and Aptar Food + Beverage

38, rue de la Princesse

CS 10509

78431 Louveciennes Cedex

France

+ 33 01 39 1720 20
Aptar Stelmi Villepinte Sales Office

Le Raspail - Paris Nord II

22, avenue des Nations

B.P. 59415, Roissy CDG Cedex

95944 Villepinte

France

+ 33 01 4863 5656
Aptar Congers Manufacturing and Sales Office

250 North Route 303

Congers, NY 10920-1408

United States of America

+ 1 845 639 3700
Aptar Suzhou Manufacturing and Sales Office

Building 24 Dongling International District

Jintian Rd., Suzhou Industrial Park Jiangsu

Suzhou 215123

China

+86 512 6593 2012 (Pharma)
Aptar Mezzovico Manufacturing and Sales Office

Via Cantonale

Mezzovico 6805

Switzerland

+ 41 91935 9090
Aptar Tortuguitas Manufacturing and Sales Office

Venezuela 3867 Tortuguitas

B1667HLC Buenos Aires

Argentina

+ 54 3 3274 52300
Aptar Mumbai Manufacturing and Sales Office

R-854, TTC, Industrial Estate

Thane- Belapur Road

Rabale Navi Mumbai

Mumbai 400701

India

+ 91 22 6195 1900 (Pharma)

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