Level Measurements in the Life Sciences Industry
What was once a laborious process is getting easier, thanks to modern sensors and calibration procedures.
Endress + Hauser provides process automation solutions for pharmaceutical companies, supporting projects ranging from pilot plants to fully automated commercial-scale facilities.
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Endress+Hauser is a global leader in measurement instrumentation, services and solutions for industrial process engineering. We provide process solutions for flow, level, pressure, analytics, temperature, recording and digital communications, optimizing processes in terms of economic efficiency, safety & environmental impact. Our customers come from various industries, including chemical, food & beverage, life sciences, power & energy, mining, minerals & metals, oil & gas and water & wastewater.
Our five product centers with headquarters in Germany and Switzerland focus on know-how in research and development, marketing, logistics, technical engineering and production. At these sites we also manufacture core components for our worldwide production. Plants in Brazil, China, France, India, Italy, Japan, the UK and the US assemble, test and calibrate instruments mainly for regional markets. This helps us to serve our customers quickly, flexibly and individually anywhere in the world.
Quality and continuous improvement is a priority at Endress+Hauser. We strive for exemplary quality in our products and services – regardless of which Endress+Hauser facility they come from. In the procurement of goods and services, we look for partnerships with suppliers that apply the same principles of quality assurance. Our management system is based on ISO 9001 and OHSAS 18001. In addition, some locations are certified based on ISO 14001 and ISO 50001.
We provide customers with hundreds of thousands of measuring points every year: virtually every device is unique, selected from a catalog with 2,000 different products and one billion available design variants. To handle this wealth of variation we use modern, highly automated production plants, which are constantly updated to meet the latest state-of-the-art standard. We rely on a qualified and highly motivated staff, offering them a broad range of training and further education opportunities.
Founded in 1953 Endress+Hauser was a true pioneer in electronic measuring technology. Since then we have continued to convince our customers with trailblazing products and solutions. Our industrial expertise and detailed application knowhow leads time and again to pioneering developments and supports our customers in the transformation into the digital future.
To ensure that our instruments can be integrated into control and asset management systems with minimum effort, we test them in a multi-vendor environment and ensure they have the appropriate certification before putting them on the market. We also develop fully instrumented solutions for particular applications, e.g. density profiling, dosing and filling, custody transfer, leakage detection, tank management etc. as well as software solutions for device and calibration management.
Endress+Hauser instruments reliably gather all of the information from the industrial process engineering processes that enable the customers to operate their plants economically and safely, to obtain optimum product quality and to protect human beings as well as the environment. But our competences go beyond the pure field instrumentation.
Today’s thriving biopharmaceutical industry demands high productivity and efficiency balanced with meticulous alignment to GMP standards. From our innovatory ASME-BPE compliant product portfolio enabling standardized production automation, reliable monitoring and predictive maintenance, to our expert consulting in process scale-up and operations optimization, Endress+Hauser offers the full solution. We speed time to market, sustain operational excellence, enhance productivity, and reduce risk.
The company offers a wide range of consistently high-quality process measurement and instrumentation products, services and solutions to reduce costs throughout the supply chain. Its products meet Good Automated Manufacturing Practice (GAMP) and International Society for Pharmaceutical Engineering (ISPE) guidelines.
Endress+Hauser is a globally qualified partner that designs and develops innovative process measurement instrumentation, solutions and services in accordance with good practice (GxP) guidelines and optimized to client requirements.
The firm’s devices offer a comprehensive range of hygienic and aseptic process connections such as Triclamp and Varivent to avoid zones where bacteria could develop, affecting product quality.
Endress+Hauser operates two Centers of Competence that provide expertise in life sciences projects. The company employs a dedicated GxP-certified life science team that has been expertly trained and that understands the challenges of the life sciences industry.
Endress+Hauser‘s products meet industry standards such as ASME BPE, GAMP 5, US Food and Drug Administration (FDA) listed materials for wetted parts (21 CFR part 177), 3-A authorization and the European Hygienic Engineering and Design Group (EHEDG), as well as have certificates for sterilize-in-place (SIP) cycles up to 150°C, materials certificates according to EN-10204, calibration certificates and standards of practice (SOP) for calibration and maintenance.
Endress+Hauser provides a comprehensive range of documentation, certificates, instructions and procedures that are GxP compliant and are mandatory for design qualification (DQ), installation qualification (IQ), operation qualification (OQ) and performance qualification (PQ).
What was once a laborious process is getting easier, thanks to modern sensors and calibration procedures.
This paper will explain how process automation has evolved and how instruments now offer integrated solutions such as Heartbeat Technology, which facilitate the implementation of 'Quality by Design' (QbD) and provide full regulatory compliance.
This paper will explain how in-situ verification technologies such as Heartbeat Technology can be used even in strictly regulated industries and be a part of a CFR part 11 compliant system.
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Pfizer will create additional manufacturing and laboratory spaces at its existing manufacturing sites in Ringaskiddy.
Eisai China has built a new oral solid dose (OSD) production facility at its new Suzhou plant in China.
In April 2018, global animal health company Zoetis began building an animal vaccine manufacturing and research complex in Suzhou, China.
In July 2008, Gedeon Richter, one of Hungary's largest pharmaceutical companies, started building a facility for the development and manufacture of biopharmaceutical products in Debrecen.
Eli Lilly made a commitment to invest approximately $400m in a biologics manufacturing facility in December 2006.
Wacker Chemie inaugurated a new production facility at its Jena site on 8 March 2010. Located approximately 90km south-w
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IDT Biologika is one of the leading biotechnology companies in Germany with its origins in the Bacteriological Institute
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Boehringer Ingelheim is a Germany-based company with interests in pharmaceuticals, biopharmaceuticals, chemicals and ani
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Roxane Laboratories has upgraded its 500,000ft² west-side pharmaceutical manufacturing plant in Columbus, Ohio, to
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Ferring Pharmaceuticals of Kiel, Wittland, Germany – a subsidiary of Ferring BV of Switzerland – began const
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Indena SpA, an Italian company based in Settala near Milan, has announced plans to automate its plant for the production
Richter Gedeon Vegyeszeti Gyar Rt, a well-known Hungarian pharmaceutical company, opened a new hormone production facili
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In September 1999 Novartis opened a new pharmaceutical production facility at the Schweizerhalle site near Basel, Switzerland.
Roche Mustahzarlari has completed the construction of their pharmaceutical facility at Gebze, close to Istanbul, Turkey.
In November 2000, Bristol-Myers Squibb began the construction of a new bulk manufacturing facility in the Republic of Ireland.
Novartis Pharmaceuticals' active pharmaceutical ingredients (API) plant complex in Grimsby, West Yorkshire, was first established in 1951.
Between 1997 and 1999, Merck Sharp and Dohme (MSD) undertook a two-year expansion of its manufacturing facility in Ballydine Co Tipperary, Ireland.
In August 2000, the Bayer Corporation was granted permission by the city of Berkeley to develop an additional 14 acres s
In April 2000, Lundbeck Pharmaceuticals was awarded contracts for the construction of a bulk pharmaceutical facility in Seal Sands, Teesside, UK.
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In 2000, biotechnology company Boehringer Ingelheim awarded Stuttgart company Life Science Meissner & Wurst an engineering contract for the expansion of its Biberach plant.
In early November 1998, Hoechst Marion Roussel (HMR) and Pfizer announced their intention to jointly develop, produce and sell inhalable insulin on a global scale.
Biochemie (now Sandoz) has invested DM85 million ($41 million) in a new Frankfurt production plant which will become the
Novo Nordisk is upgrading the insulin production plant at its facility in Chartres, Eure-et-Loir region, France. The Dan
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Endress+Hauser Flow’s calibration laboratory has been accredited in compliance with ISO/IEC 17025 since 1994. From this moment onwards, the flowmeter manufacturer has not only reinforced its capabilities and core competences but has also confirmed its position as a market leader consistently providing services of excellence.
SICK and Endress+Hauser are bringing their strategic partnership in process automation to life: SICK’s advanced gas analysis and flow measurement technology is now an integral part of Endress+Hauser’s comprehensive instrumentation portfolio. The collaboration is designed to offer customers in the process industry enhanced support in increasing plant efficiency, protecting the environment and reducing carbon footprint.
Proline Promass U 500 from Endress+Hauser is the first fully cGMP-compliant Coriolis flowmeter for biotechnology
Companies sign joint memorandum of understanding for a strategic partnership
Endress+Hauser has built a state-of-the-art production facility at its Aurangabad site
70 years of Endress+Hauser: customer forum, internal conferences and employee party in Basel
Group drives corporate social responsibility and joins Science Based Targets initiative.
Endress+Hauser’s load test of a realistic setup confirms the new technology’s performance
Endress+Hauser joins the European Clean Hydrogen Alliance
Group exceeds own expectations in the 2021 financial year
Endress+Hauser is one of Switzerland’s top ten innovative companies.
Depending on the application, a field instrument is required to measure and control different automation processes. This is why Endress+Hauser's field instruments use different measuring principles to operate reliably and accurately in any situation.
Endress+Hauser's commitment to you is to support, to service and to optimise your process.
The Field Xpert SMT70 tablet PC for device configuration enables mobile plant asset management in hazardous and non-hazardous areas.
The Liquiline Compact CM82 is the smallest transmitter for Memosens sensors.
Micropilot FMR62 is the first 80GHz radar developed according to the international functional safety directive IEC 61508.
Promass P 100 offers the enhanced performance of a bent tube meter and the drainability of a straight tube meter without any compromise.
The iTHERM TrustSens TM371 and TM372 compact hygienic thermometer is designed for applications in the life sciences and food and beverage industries that require seamless compliance to FDA regulations and/or GMP rules
The Proline Promass U 500 Coriolis flowmeter from Endress+Hauser is designed for carrying out biotechnological single-use processes in compliance with current good manufacturing practice (cGMP) criteria. It offers accuracy, precision and traceable calibration, as well as simple handling and a clear user interface.
Endress+Hauser’s Cerabar PMP43 is a pressure measurement solution that offers a wide range of sensor variants. The device features fully welded, hygienic process connections as used prominently in the food and beverage and life sciences industries.
Switzerland has a sense of tradition and passion for technology. Endress + Hauser combines both. It began as pioneers of electronic sensor technology in 1953.
Klaus Köhler's task is to bring Endress + Hauser customers as close as possible to the company to develop the right instruments, solutions, and services that provide the most value.
Our service expert talks about the importance of calibration in the life sciences industry and how Endress+Hauser can help you optimize your calibration intervals and manufacturing continuity.
Our temperature expert Dietmar Saecker explains how the latest innovation in temperature measurement can save costs in biopharmaceutical manufacturing.