Multisorb Technologies Protecting Pharma Packaging from Moisture, Oxygen and Hydrocarbons

multisorb

With more than 50 years’ experience in the active packaging industry, Multisorb Technologies has the expertise to deliver proven solutions for the management of moisture, oxygen, hydrocarbons, and other volatiles in healthcare product packaging.

As a long time supplier to the healthcare industry, Multisorb’s products are extensively used to ensure the stability of pharmaceutical, in-vitro diagnostic, medical device, dietary supplement, and drug delivery products.

Product stability solutions from design to dispensing

Multisorb’s seasoned team of packaging professionals, chemists, biochemists, and engineers provide skilled resources to understand and solve virtually any product stability issue. Using the quality by design (QbD) based Calculations through Operations® programme, they can assist you by providing a consultative approach to determining sorbent requirements by examining the entire development process from design through dispensing.

This ensures the decisions made by formulation chemists in the developmental stages complement processes later on in the product packaging stages. The programme takes a multi-step approach, calculating exact sorbent formulations, developing the proper sorbent configuration, and, finally, delivery of the sorbent solution.

Solutions to predict physical and chemical stability of healthcare products

Multisorb formulates your optimized sorbent product using its proprietary SimulSorb™ and SimulOx™ pseudo-empirical modeling programmes, which help predict physical and chemical stability outcomes for healthcare products, devices, or device components in their packaging. In the case of moisture, the SimulSorb modeling programme can predict the equilibrium relative humidity (ERH) in the package headspace and drug product free-moisture level for the shelf-life of the product.

Similarly, the SimulOx programme provides an approach for the management of oxygen in healthcare packaging. For example, when maintaining the stability of a drug product formulation requires controlling the oxygen concentration in a pharmaceutical package’s headspace over time.

In addition to moisture and oxygen, hydrocarbons often need to be managed as well. Organic solvents that are used may volatilize releasing these hydrocarbons into the drug product package that can also lead to chemical degradation or unwanted interaction with some packaging materials. While this can sometimes relate to a product stability issue, the goal of hydrocarbon management is usually odor control.

Removing moisture and oxygen from medical packaging

In some instances there is a need to remove moisture and oxygen while managing specific volatilized hydrocarbons in the package headspace. Or there might be a need to manage moisture, maintaining a specific relative humidity, as opposed to aggressive desiccation. This is where multifunctional IntelliSorb® intelligent sorbent formulations have proven to be effective.

Once an optimized sorbent formulation is determined, it is presented in a Drop-In, Fit-In, or Built-In format that is most suitable for the product’s needs. Multisorb’s Drop-In sorbent solutions offer the management of moisture, oxygen, odors, and/or volatilized hydrocarbons in secondary packaging. A drop-in solution consists of sorbent in a packet or canister format, which would be placed inside the pouch or bottle.

Moisture protection solutions

Fit-In solutions are compressed form sorbents that are formed to fit within a specific space in a device or packaging. Fit-In solutions can deliver greater moisture protection in the same dimensional space, significantly increasing the level of functional moisture management per unit volume.

With Built-In solutions, sorbent material is incorporated right into an existing thermoplastic component allowing for sorbent protection in products that otherwise have no available space for sorbent application. This technologically advanced solution creates a moisture management solution that is invisible to the consumer.

To round out the Calculations through Operations Programme, the customized Drop-In sorbent can be inserted into your drug product packaging using its corresponding APA-series sorbent dispenser. Multisorb’s systems-based sorbent/dispenser approach provides unparalleled accuracy, reliability, and efficiency while providing the most effective solution for ensuring stability throughout the desired shelf life of your product.

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Press Release

Multisorb to Exhibit Medical Spill and Liquid Containment Solutions

Multisorb Technologies will exhibit its medical spill and liquid containment solutions at the AORN Surgical Conference & Expo in Anaheim, California from 3-6 April.

White Papers

StabilOx® System

The StabilOx System is a turnkey solution that brings together the advantages of StabilOx® Oxygen Absorbing Packets or Canisters with the proven reliability of the company's APA-series dispensing equipment.

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Multisorb Technologies

Buffalo Site & Corporate Offices

325 Harlem Road

Buffalo

14224

New York

United States of America

+1 716 824 8900 +1 716 824 4128 www.multisorb.com

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Press Release

24 February 2016

Multisorb Technologies will exhibit its medical spill and liquid containment solutions at the AORN Surgical Conference & Expo in Anaheim, California from 3-6 April.

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2 November 2015

Multisorb has launched the PolySorb desiccant card, a low-profile desiccant for managing moisture.

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2 October 2015

Multisorb Technologies will be showing how its Success through Efficiency programme helps companies quickly identify, select, and dispense the optimal sorbent at the American Association of Pharmaceutical Scientists (AAPS) Meeting and Exposition.

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23 September 2015

Multisorb Technologies will be attending InnoPack from 13-15 October in Madrid, Spain.

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18 September 2015

Multisorb will exhibit at Pack Expo in Las Vegas from 28-30 September.

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3 July 2015

Multisorb Technologies will highlight its medical spill and liquid containment solutions at the AHRMM15 Conference and Exhibition in Indianapolis, Indiana from 9-12 August at booth 427.

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27 May 2015

Multisorb Technologies has appointed Irene Low to the position of business development leader of Healthcare Packaging East Asia and Australia.

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20 May 2015

Multisorb will attend Pharmapack North America from 9-10 June at the Jacob K Javits Convention Center, New York, to highlight how the efficiencies of its sorbent dispensing systems and simulation technology can help pharmaceutical companies and drive profitability.

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15 April 2015

Multisorb Technologies will attend RDD Europe in Antibes, France, from 5-8 May 2015.

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27 March 2015

Multisorb Technologies has announced it will be exhibiting at Interphex in New York.

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19 February 2015

Multisorb Technologies will exhibit its medical spill and liquid containment solutions at AORN Surgical Conference and Expo in Denver, Colorado.

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5 February 2015

Multisorb Technologies has announced it will exhibit its sorbent technology and solutions at MD&M West from February 10-12 2015, in Anaheim, California.

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22 January 2015

Mr Alex Jan Wagteveld will be the new business development leader, Northern Europe, at Healthcare Packaging, as part of Multisorb's global expansion.

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2 December 2014

Multisorb Technologies will be attending CPhI and P-MEC India exhibition from 2-4 December.

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24 November 2014

Peter Lirusso has been appointed business development leader of Healthcare Packaging Canada.

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24 October 2014

Multisorb Technologies will be presenting a technical poster at the 2014 American Association of Pharmaceutical Scientists (AAPS) Meeting and Exposition at San Diego Convention Center in San Diego.

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Regional Offices

Multisorb Technologies

Buffalo Site & Corporate Offices

325 Harlem Road

Buffalo

14224

New York

United States of America

+1 716 824 8900 +1 716 824 4128 www.multisorb.com

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