In order to get the best therapeutic effect possible out of drugs, researchers are continuously seeking to improve drug delivery and coming up with new methods and systems that allow for medicines to be better targeted and more readily absorbed.

From nanoscale targeting to controlled-release systems, we profile some of the most advanced drug delivery technologies already available, as well as promising research that may help to bring the next generation of ever more effective therapies to the market.

We find out how scientists are using nanotechnology to deliver therapeutic molecules directly into a patient’s infected cells without harming other cells, and look at sophisticated injectable depot systems for controlled-release drugs. We also profile the latest developments in solubility enhancement and explore leading technologies in the fast-advancing sector of prefilled syringe systems.

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Taking Aim with Nanotechnology

One of the key challenges of drug delivery is ensuring the right dose reaches the target without damaging healthy cells. Richard Moore of the Institute of Nanotechnology and former MIT researcher Geoffrey von Maltzahn tell us why downsizing drug delivery to the nanoscale helps scientists pull off this balancing act.
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Boosting Bioavailability

Poor solubility can be critical for otherwise life-saving drugs, but new information could herald a welcome solution. We speak to John Comer of Sirius Analytical and Dr Woei Ping Cheng of the University of Hertfordshire about the latest developments in the fast-advancing field of solubility enhancement
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Getting to the Point

As the pharmaceutical industry continues to seek out drug delivery methods that improve safety and efficiency while reducing costs, the traditional multi-dose or single-dose vial format for vaccines and injectables is starting to show its age. We examine the finely-honed science behind ready-to-use syringes as they continue to fuel one of the medical device industry’s fastest-growing markets.
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Taking Control

Controlled-release drugs can have many benefits, particularly for patients with chronic or autoimmune diseases. But ongoing research has revealed that this market’s potential is only now about to take off, as professors Patrick P DeLuca and Heidi M Mansour explain.
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Child’s Play

The paediatric drugs market is growing rapidly, but is a lack of guidance putting children at risk? We shed some light on the restrictions surrounding paediatric drug development, the pitfalls of inaccurate medication and the ethical issues involved in infant clinical trials.
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Next Issue: Clinical Trials

The management of clinical trials is a long and costly process, involving many parties providing and requiring information at different times. In the next issue we explore the trends and issues surrounding clinical trials and the strategies and technology that can help to achieve successful and cost-efficient trials.

We investigate current trends in outsourcing of drug trials, and ask experts about the best strategies for selecting trial sites that can meet equipment, staff and patient requirements. We also find out how imaging biomarkers could help to speed up the process of getting new drugs to patients, and explore how the advent of cloud computing can improve the efficiency and security of clinical trials.

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