Medelpharm Tablet Press Solution for Powder Compaction Analysis and Manufacture


Medelpharm is a high-precision engineering company manufacturing research and development (R&D) tablet presses and providing innovative solutions for powder analysis and formulation.

The company focuses on continuous development of innovative research presses (hardware and software), simulation of industrial production cycles, powder characterisation and formulation services, compression, and material science in the pharmaceutical, food, and cosmetics markets.

Research press for the characterisation of raw materials and formulations for tablet development

The new STYL’One Evolution tableting instrument is a high-speed, all-in-one multilayer tool designed for use in tablet development from early formulation to scale-up at production speed.

The machine characterises essential powder properties and active pharmaceutical ingredients (API). It tests their suitability by simulating industrial production cycles, typically up to 400,000 tab/hour (dwell time <2ml), with only a few grams of powder needed.

No compromise on user protection from early research to multilayer production scale-up

Following a global trend, Medelpharm offers different levels of operator protection from wash-in-place to full containment OEL 5 for the most potent drug substances.

Small-scale development in dry granulation

Dry granulation with roll compaction hybrid modelling is a topic intensively pursued by Medelpharm in close cooperation with the University of Düsseldorf.

QbD is at the heart of the development of tablet formulation

Quality by Design (QbD) is a concept to produce a drug in a repeatable and cost-effective way. This concept is in the heart of the design of the STYL’One R&D press.

High-power, adaptable software for powder compaction analysis

The ANALIS data acquisition and control package automatically explores and analyses the design of formula with efficiency in investigating critical attributes.

Collected data is analysed and presented in a user-friendly tabular or graphical format.

Compaction of tablets and analysis of powder properties but no trade-off in ease-of-use

The STYL’One Evolution is easy to use, with a compact, door-size design. It offers a clean and easy exchange of B, D (EU │TSM) oversized, core rods.

Valuable accessories are available such as the micro-dosing unit, a tab-in-tab device, a good manufacturing practice (GMP) module with weight regulation and force feeding, and a heated die.

STYLCAM / STYL’One has been installed more than 100 times worldwide.

Training to maximise capabilities in R&D and production

Medelpharm offers a range of training courses that are recognised by French authorities. The company aims to offer its extensive knowledge through effective training.

Medelpharm also offers its professional tableting instruments to various universities for training purposes so students can gain experience on current and future working methods. The company has university partnerships worldwide.

Maintenance, FAT, and SAT

Medelpharm offers services such as URS definition, installation, FAT, SAT, training and support, maintenance, and calibration, as well as consumables and wear and tear parts.

Powder processing solutions

Medelpharm distributes renowned and innovative technologies in powder processing from lab-scale to production with brands such as supplier of special process machines LB Bohle, manufacturer and developer of equipment for the production of pellets Caleva, and manufacturer of pharmaceutical hammer mills Fitzpatrick.

Conical mill for consistent size reduction and uniform tableting

Quadro is a tableting machine designed to provide uniform tableting. It evenly reduces the size of materials and has sieving, dispersion, and deagglomaration abilities.

Procept is a lab-scale R&D machine that specialises in drying, tablet coating, agglomeration, and mixing applications.

About Medelpharm

Medelpharm is headquartered in Lyon, South-East France. Its team of experienced scientists provide powder characterisation services for screening of numerous formulations and testing powder flowability, powder densities, and tabletability.

In mid-2017, Medelpharm decided to leave its laboratory in the heart of the University of Lyon and built a laboratory on its own premises. This laboratory has a controlled atmosphere so it can perform powder characterisation and analysis. It also houses innovative measuring equipment such as the STYL’One Tableting Instrument, Smart test 50, a mini coater / drier for coating of minimal quantities of tablets, and an SLS multifunctional mill and sifter.

Distribution of the STYL’One Tableting instrument is part of a global partnership with the Romaco Group.

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Press Release

Medelpharm’s Success at AAPS, San Diego

Hundreds of attendees found their way to the tool in the jungle of formulation at AAPS booth 2003: The STYL’One Tableting Instrument LIVE.

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12, rue des petites Combes,

Z.I. Nord

F-01700 Beynost


+33 478 976 210 +33 478 88 18 65 Company Video: External lubrication on STYL'One Evolution

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Products and Services


Press Release

30 November 2017

Hundreds of attendees found their way to the tool in the jungle of formulation at AAPS booth 2003: The STYL’One Tableting Instrument LIVE.

Read more
9 October 2017

Medelpharm has announced it will be showcasing the renowned STYL'One Evolution tableting instrument with its latest innovative accessories at CPhI Frankfurt.

Read more

Regional Offices


12, rue des petites Combes,

Z.I. Nord

F-01700 Beynost


+33 478 976 210 +33 478 88 18 65 Company Video: External lubrication on STYL'One Evolution

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