PHARMATRANS SANAQ Excipients and Value Added Active Ingredients (API)

PHARMATRANS SANAQ specialises in innovative and multifunctional excpients for solid dosage forms as well as in value added APIs for pharmaceuticals. As a partner for the pharmaceutical industry, we have been working in this field for over 25 years. Our aim is to provide the industry with customised products and solutions. We continuously search and develop new excipients, or better forms of existing excipients, based on the needs of our partners in the industry.

MCC SANAQburst – multifunctional excipient as binder, filler and superdisintegrant

MCC SANAQburst consists of 100% pure microcrystalline cellulose (no additional excipients). The fast disintegration remains even after wet granulation and extrusion processes. With MCC SANAQburst reduction of excipients in a formulation can be achieved, fast disintegration tablets, dispersible and ODTs as well as fast dissolving pellets by extrusion / spheronisation.

Microcrystalline cellulose pellets – neutral starter core

CELLETS microcrystalline cellulose pellets are a neutral starter of 100% microcrystalline cellulose. As inert carriers, CELLETS are mainly used for controlled release formulations and for innovative drug delivery, already being available from below 100µm. The product characteristics lead to a reproducible and reliable production process.

The advantages of CELLETS include:

  • The wide range of particle size fractions with uniform spherical shape and structure (100µm – 1,400µm)
  • Narrow particle size distribution within each fraction
  • Formulation of sensitive actives, due to the inertness of MCC
  • High abrasion resistance, which improves the coating process
  • Excellent compactability, due to the high plasticity of the CELLETS, for formulation of multidosage tablets
  • Higher payload permits smaller capsule sizes

Carnauba Wax pellets as hydrophobic, neutral starter core

C-Wax Pellets constist of 100% Carnauba Wax. In some formulations a hydrophobic core is needed to achieve a specific dissolution profile. C-Wax Pellets do not require an additional subcoating to achieve this effect and other starter cores.

Sugar Spheres as neutral starter core

Sugar Spheres Sanaq are sugar non-pareils – neutral starter cores for the production of controlled release formulations or for direct compression to ensure the content uniformity of low dosage API in tablets.

Mannitol pellets as neutral starter core

MCELL consist of 100% Mannitol and are non-hygroscopic, highly spherical, dense and have a low attrion to be used as alternative water soluble starter core for pellet formulations.

Tartaric Acid pellets as functional starter core

TAP are spherical cores and consist of 100% Tartaric Acid. TAP act as a pH-modifier for substances (e.g. weakly basic drugs) with a poor solubility in higher pH that occur in the lower GIT. TAP enhance the solubility in this environment.

  • TAP 200: 100-350 micron
  • TAP 400: 300-500 micron
  • TAP 500: 400-600 micron

Microcrystalline cellulose

Microcrystalline cellulose MCC SANAQ is a purified and partially depolymerised a-cellulose widely used as filler, binder and granulation aid for tablets, granules and in capsules. Different types for wet granulation, dry granulation and direct compression are available – MCC SANAQ 101L, 102L, 200L, 301L, 302L.

MCC SANAQ UL-002 compactible binder

MCC SANAQ UL-002 is a highly compactible binder. Thanks to its low bulk density and different particle shape, the compactablity is significantly enhanced compared to standard MCC types. This leads to lower compression forces in case of pressure sensitive formulations and higher drug loading (or smaller sized tablets with the same drug loading) thanks to the reduction of excipient. The product portfolio also includes:

Sodium starch glycolate superdisintegrant

SSG SANAQ is a super disintegrant for tablets, capsules and granules.

Sodium stearyl fumarate lubricant

LubriSanaq is a high-quality lubricant for tablet and capsule formulations.

100% Ibuprofen pellets for direct compression

Ibuprofen DC 100 is an optimised Ibuprofen to perform high-speed tableting processes, overcoming sticking and picking behaviour.

Acetylsalicylic acid solvent-free coated

ASACOAT SANAQ is a lipid coated acetylsalicylic acid to enhance the stability of the API by moisture protection.

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Press Release

Cellets® – Neutral Starter Cores of Microcrystalline Cellulose

Cellets® are neutral carriers for pellet systems in controlled release formulations. As an inert and insoluble core Cellets combine unique product and process properties and offer a wide range of particle sizes. The standard types start with Cellets 100 (100µm-200µm) and

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PHARMATRANS SANAQ AG

Birsigstrasse 79

CH-4011

Other

Switzerland

+41 61 225 9000 +41 61 225 9001 www.pharmatrans-sanaq.com

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Press Release

26 June 2011

Cellets® are neutral carriers for pellet systems in controlled release formulations. As an inert and insoluble core Cellets combine unique product and process properties and offer a wide range of particle sizes. The standard types start with Cellets 100 (100µm-200µm) and

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5 April 2011

PHARMATRANS SANAQ welcomes you to the 8th Scientific & Technical Forum, 'Innovative Drug Delivery Systems', which will be held in Basel, Switzerland, on 12 and 13 May 2011. Thursday 12 May 2011 Conference programme 8.45am-5pm: Prof. Andreas Bernkop-Sc

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3 April 2011

ASACOAT SANAQ is obtained by hot-melt coating of acetylisalicylic acid with glyceryl behenate. The natural coating enhances the stability of Aspirin based on the hydrophobic characteristics of the glyceryl behenate. ASACOAT SANAQ is easy to formulate as it can be directly compressed aft

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7 November 2009

Pharmatrans Sanaq (founded in 1982) is today specialised in pharmaceutical excipients and novel drug vehicles such as pellets for solid dosage form design. The focus has initially been set on standard types of microcrystalline cellulose and the further development thereof. These develop

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5 October 2009

At CPHI in Madrid, Pharmatrans Sanaq will present its universally applicable microcrystalline cellulose that acts as a binder, filler and disintegrant in tablet, pellet and capsule formulations. The MCC SANAQ®burst consists of 100% microcrystalline cellulose. It will be demonstrated at Pharm

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29 November 2008

Pharmatrans Sanaq has announced its sixth Scientific and Technical Forum, dedicated to trends in formulation design. The forum takes place on 19-20 February 2009 in Basel, Switzerland. The first day event is composed of the following lecturers: Ajaz S. Hussain, vice president,

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12 November 2008

Cellets are neutral starter cores for controlled release formulation. The spheres consist of 100% microcrystalline cellulose and combine physical properties, such as high sphericity, mechanical strength and narrow particle size distribution, for an optimal formulation and production process.

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25 June 2008

Cellets® are neutral carriers for pellet systems in controlled release formulations. As an inert and insoluble core Cellets combine unique product and process properties and offer a wide range of particle sizes. The standard types start with Cellets 100 (100-200µm) and end with Cell

Read more
20 June 2008

LubriSanaq® sodium stearyl fumarate is an inert, hydrophilic lubricant for tablets and capsules. LubriSanaq provides solutions where other lubricating agents fail in providing tablets of adequate stability, hardness, content uniformity and show difficulties with disintegration and d

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8 June 2008

OroCell is a spheronised mannitol compound with outstanding characteristics as a binder, filler and carrier in immediate release oral dispersible tablet (ODT) preparations. OroCell has exceptional processing features as a result of innovative spheronisation technologies. In addition it

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5 February 2008

LubriSanaq® Sodium Stearyl Fumarate is an inert, hydrophilic lubricant for tablets and capsules. LubriSanaq provides solutions where other lubricating agents fail in providing tablets of adequate stability, hardness, content uniformity and show difficulties with disintegration and

Read more
20 January 2008

The 4th Scientific & Technical Forum "How can we reduce time to market and enhance product quality?" organised by PHARMATRANS SANAQ AG will take place on April 17th and 18th at the Hotel Bildungszentrum 21 in Basel/Switzerlad. The event is hosted by Prof Hans Leuenberger, Ifiip GmbH

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26 July 2007

IBUPROFEN DC100 (Ph. Eur / USP-NF) are spherically shaped particles consisting of Ibuprofen drug substance. IBUPROFEN DC100 is the unique directly compressible form of Ibuprofen which consists of 100% pure drug substance with no additional excipients. Due to its shape and sur

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26 July 2007

IBUPROFEN DC100 (Ph. Eur / USP-NF) are spherically shaped particles consisting of 100% Ibuprofen drug substance. IBUPROFEN DC100 is the unique directly compressible form of Ibuprofen which consists of 100% pure drug substance with no additional excipients. Due to its shape and surface

Read more
7 July 2007

Cellets® are neutral carriers for pellet systems in controlled release formulations. As an inert and insoluble core Cellets combine unique product and process properties and offer a wide range of particle sizes. The standard types start with Cellets 100 (100-200µm) and end with Cellets

Read more
21 June 2007

MCell is the long-desired, 100% sugar-free water soluble substitute for sugar spheres in drug layering and coating. The controlled and narrow particle size distribution favours reproducible dissolution behaviour of substances manufactured with MCell products. The MCell spheres consist o

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19 June 2007

The newly developed spheronised pharmaceutical Mannitol products combine the unique and well acknowledged characteristics of compendial Mannitol with exceptional processing features as a result of innovative spheronisation technologies. OroCell types 200 and 400 are mainly used in direc

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19 December 2006

The 4th Scientific & Technical Forum, Innovative Dosage Forms & Process Technlogy, organised by PHARMATRANS SANAQ AG will take place on 15th and 16th March, 2007 at Hotel Bildungszentrum 21 in Basel Switzerland. The event is hosted by Prof. Hans Leuenberger and the topics are co

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30 November 2006

MCC SANAQ® UL-002 is a purified and partially depolymerized cellulose whose chemical and physical identities meet the international standards of microcrystalline cellulose (Ph. Eur / USP-NF). Its unique properties makes it a highly compactible binder. MCC SANAQ standard types are k

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Regional Offices

PHARMATRANS SANAQ AG

Birsigstrasse 79

CH-4011

Other

Switzerland

+41 61 225 9000 +41 61 225 9001 www.pharmatrans-sanaq.com
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