PHARMATRANS SANAQ

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Excipients and Value Added Active Ingredients (API)

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Birsigstrasse 79,
CH-4011,
Other,
Switzerland
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PHARMATRANS SANAQ specialises in innovative and multifunctional excpients for solid dosage forms as well as in value added APIs for pharmaceuticals. As a partner for the pharmaceutical industry, we have been working in this field for over 25 years. Our aim is to provide the industry with customised products and solutions. We continuously search and develop new excipients, or better forms of existing excipients, based on the needs of our partners in the industry.

MCC SANAQburst – multifunctional excipient as binder, filler and superdisintegrant

MCC SANAQburst consists of 100% pure microcrystalline cellulose (no additional excipients). The fast disintegration remains even after wet granulation and extrusion processes. With MCC SANAQburst reduction of excipients in a formulation can be achieved, fast disintegration tablets, dispersible and ODTs as well as fast dissolving pellets by extrusion / spheronisation.

Microcrystalline cellulose pellets – neutral starter core

CELLETS microcrystalline cellulose pellets are a neutral starter of 100% microcrystalline cellulose. As inert carriers, CELLETS are mainly used for controlled release formulations and for innovative drug delivery, already being available from below 100µm. The product characteristics lead to a reproducible and reliable production process.

The advantages of CELLETS include:

PHARMATRANS SANAQ is specialised in excipients for solid dosage forms.
SSG SANAQ is used as a disintegrant for tablets, capsules and granules.
CELLETS are the perfect tool for the layering application in controlled release products.
CELLETS used in multiple dosage forms mean more reliable formulations thanks to the homogeneous concentration of highly active agents.
  • The wide range of particle size fractions with uniform spherical shape and structure (100µm – 1,400µm)
  • Narrow particle size distribution within each fraction
  • Formulation of sensitive actives, due to the inertness of MCC
  • High abrasion resistance, which improves the coating process
  • Excellent compactability, due to the high plasticity of the CELLETS, for formulation of multidosage tablets
  • Higher payload permits smaller capsule sizes

Carnauba Wax pellets as hydrophobic, neutral starter core

C-Wax Pellets constist of 100% Carnauba Wax. In some formulations a hydrophobic core is needed to achieve a specific dissolution profile. C-Wax Pellets do not require an additional subcoating to achieve this effect and other starter cores.

Sugar Spheres as neutral starter core

Sugar Spheres Sanaq are sugar non-pareils – neutral starter cores for the production of controlled release formulations or for direct compression to ensure the content uniformity of low dosage API in tablets.

Mannitol pellets as neutral starter core

MCELL consist of 100% Mannitol and are non-hygroscopic, highly spherical, dense and have a low attrion to be used as alternative water soluble starter core for pellet formulations.

Tartaric Acid pellets as functional starter core

TAP are spherical cores and consist of 100% Tartaric Acid. TAP act as a pH-modifier for substances (e.g. weakly basic drugs) with a poor solubility in higher pH that occur in the lower GIT. TAP enhance the solubility in this environment.

  • TAP 200: 100-350 micron
  • TAP 400: 300-500 micron
  • TAP 500: 400-600 micron

Microcrystalline cellulose

Microcrystalline cellulose MCC SANAQ is a purified and partially depolymerised a-cellulose widely used as filler, binder and granulation aid for tablets, granules and in capsules. Different types for wet granulation, dry granulation and direct compression are available – MCC SANAQ 101L, 102L, 200L, 301L, 302L.

MCC SANAQ UL-002 compactible binder

MCC SANAQ UL-002 is a highly compactible binder. Thanks to its low bulk density and different particle shape, the compactablity is significantly enhanced compared to standard MCC types. This leads to lower compression forces in case of pressure sensitive formulations and higher drug loading (or smaller sized tablets with the same drug loading) thanks to the reduction of excipient. The product portfolio also includes:

Sodium starch glycolate superdisintegrant

SSG SANAQ is a super disintegrant for tablets, capsules and granules.

Sodium stearyl fumarate lubricant

LubriSanaq is a high-quality lubricant for tablet and capsule formulations.

100% Ibuprofen pellets for direct compression

Ibuprofen DC 100 is an optimised Ibuprofen to perform high-speed tableting processes, overcoming sticking and picking behaviour.

Acetylsalicylic acid solvent-free coated

ASACOAT SANAQ is a lipid coated acetylsalicylic acid to enhance the stability of the API by moisture protection.

Press Releases

  • Cellets® - Neutral Starter Cores of Microcrystalline Cellulose

    Cellets® are neutral carriers for pellet systems in controlled release formulations. As an inert and insoluble core Cellets combine unique product and process properties and offer a wide range of particle sizes. The standard types start with Cellets 100 (100µm-200µm) and

  • ASACOAT SANAQ - Solvent-Free Coated Aspirin

    ASACOAT SANAQ is obtained by hot-melt coating of acetylisalicylic acid with glyceryl behenate. The natural coating enhances the stability of Aspirin based on the hydrophobic characteristics of the glyceryl behenate. ASACOAT SANAQ is easy to formulate as it can be directly compressed aft

  • Sixth Scientific and Technical Forum: "Trends in Formulation Design"

    Pharmatrans Sanaq has announced its sixth Scientific and Technical Forum, dedicated to trends in formulation design. The forum takes place on 19-20 February 2009 in Basel, Switzerland. The first day event is composed of the following lecturers: Ajaz S. Hussain, vice president,

  • News on Cellets - Microcrystalline Cellulose Spheres

    Cellets are neutral starter cores for controlled release formulation. The spheres consist of 100% microcrystalline cellulose and combine physical properties, such as high sphericity, mechanical strength and narrow particle size distribution, for an optimal formulation and production process.

  • Cellets - the Neutral Starter Cores Made of Microcrystalline Cellulose

    Cellets® are neutral carriers for pellet systems in controlled release formulations. As an inert and insoluble core Cellets combine unique product and process properties and offer a wide range of particle sizes. The standard types start with Cellets 100 (100-200µm) and end with Cell

  • LubriSanaq - More Than a Tablet Lubricant

    LubriSanaq® sodium stearyl fumarate is an inert, hydrophilic lubricant for tablets and capsules. LubriSanaq provides solutions where other lubricating agents fail in providing tablets of adequate stability, hardness, content uniformity and show difficulties with disintegration and d

  • Orocell – The Excipient for ODT Formulations

    OroCell is a spheronised mannitol compound with outstanding characteristics as a binder, filler and carrier in immediate release oral dispersible tablet (ODT) preparations. OroCell has exceptional processing features as a result of innovative spheronisation technologies. In addition it

  • LubriSanaq® - Sodium Stearyl Fumarate

    LubriSanaq® Sodium Stearyl Fumarate is an inert, hydrophilic lubricant for tablets and capsules. LubriSanaq provides solutions where other lubricating agents fail in providing tablets of adequate stability, hardness, content uniformity and show difficulties with disintegration and

  • IBUPROFEN DC100 - a Novel Grade for Direct Compression

    IBUPROFEN DC100 (Ph. Eur / USP-NF) are spherically shaped particles consisting of 100% Ibuprofen drug substance. IBUPROFEN DC100 is the unique directly compressible form of Ibuprofen which consists of 100% pure drug substance with no additional excipients. Due to its shape and surface

  • Cellets® - Microcrystalline Cellulose Pellets

    Cellets® are neutral carriers for pellet systems in controlled release formulations. As an inert and insoluble core Cellets combine unique product and process properties and offer a wide range of particle sizes. The standard types start with Cellets 100 (100-200µm) and end with Cellets

  • MCell Spheres - Mannitol Spheres for Layering and Coating

    MCell is the long-desired, 100% sugar-free water soluble substitute for sugar spheres in drug layering and coating. The controlled and narrow particle size distribution favours reproducible dissolution behaviour of substances manufactured with MCell products. The MCell spheres consist o

  • OroCell - Spherical Mannitol for Direct Compression

    The newly developed spheronised pharmaceutical Mannitol products combine the unique and well acknowledged characteristics of compendial Mannitol with exceptional processing features as a result of innovative spheronisation technologies. OroCell types 200 and 400 are mainly used in direc

  • Innovative Dosage Form & Process Technology Forum

    The 4th Scientific & Technical Forum, Innovative Dosage Forms & Process Technlogy, organised by PHARMATRANS SANAQ AG will take place on 15th and 16th March, 2007 at Hotel Bildungszentrum 21 in Basel Switzerland. The event is hosted by Prof. Hans Leuenberger and the topics are co

Address
PHARMATRANS SANAQ AG
Birsigstrasse 79
CH-4011
Other
Switzerland

Phone
Fax Number