Contract Pharmaceutical Development Services and Commercial Manufacturing
With a commitment to quality, scientific excellence and exceptional customer experiences, Patheon is the world's leading provider of contract pharmaceutical development services and commercial manufacturing.
Make an enquiry
Subscribed
You have successfully submitted your enquiry. Someone from our company will respond ASAP
Patheon specialises in pharmaceutical development and manufacturing services.
Active pharmaceutical ingredients (API) for the pharmaceutical sector
Patheon provides an integrated and customizable range of active pharmaceutical ingredients (API) and finished drug product services, including formulation development, clinical and commercial-scale manufacturing, packaging, and lifecycle management.
The company’s services address small and large molecule biological drugs.
Patheon is an end-to-end integrated provider, which combines scientific and regulatory expertise and specialised capabilities. This provides clients with a single outsourced provider to address complex development and manufacturing challenges.
Early Development: We deploy advance technologies for characterization of drug substances, evaluation of formulation options and to set a clear path to in-vitro, preclinical and first-in-man studies.
Late Development: Expertise in all stages of development makes us uniquely capable of developing formulations and processes that ensure future manufacturability and repeatable quality.
Commercial Supply: Consistent on-time delivery, dependable quality and depth of expertise have made Patheon the industry’s leading supplier of contract commercial supply services.
Solid Dose Forms: Patheon offers a remarkable range of conventional solid dose forms as well as specialized combinations and controlled release technologies.
Sterile Products: We offer extensive sterile product development and commercial manufacturing capabilities, including world-class expertise in lyophilization and ready-to-use dose formats.
High Potency: Customers with highly potent compounds, such as hormones, get the same flexibility, quality, expertise and breadth of resources as all Patheon customers.
Biologics: With the experience of more than 94 biologic development projects, we offer a broad range of capabilities and resources – often within a single site – to achieve the most effective formulation.
Quick to Clinicâ„¢: For a fixed price and guaranteed four-month timeline, you can have a solid dose molecule formulated into clinical material for first-in-man (Phase I) studies.
Patheon Certified Consultants: CMC guidance, transaction diligence support, and decision acceleration from top independent consultants behind over 200 products and 2,000 IND submissions.
Patheon specialises in leading product development services and commercial-scale product manufacturing.
Development and manufacturing solutions
Patheon transforms the pharmaceutical supply chain model with innovative, flexible, and customised end-to-end development, as well as manufacturing solutions that reduce complexity and shorten time-to-market.
Clients gain access to a wide range of drug substances, pharmaceutical development, and drug product solutions for large and small molecules, including an array of oral solid, sterile, and softgel dosage forms.
This provides flexibility to choose the most appropriate chemistry, manufacturing, and controls (CMC) technologies with the confidence that the programme will be delivered on time.
The company employs new business models to help clients simplify their supply chain management activities in an increasingly complex drug development industry.
Drug substance and drug product services
Patheon is organized into three distinct business units, drug substance services (DSS), pharmaceutical development services (PDS), and drug product services (DPS).
DSS is one of the top three outsourced manufacturers of highly complex biological drug substance produced in four biological API facilities. These sites are positioned to serve 70% of the market.
Patheon provides complex small molecule APIs and flexible outsourced manufacturing solutions for large molecule biologic APIs from early development through to commercial-scale production.
PDS Patheon is a leading global provider of formulation services. The company’s capabilities span the full breadth of advanced scientific services, including discovery, regulatory approval and formulation development across 40 dosage forms, as well as analytical services and life-cycle management.
DPS Patheon has developed and manufactured 20% of the top 100 drugs and 75% of the dosage forms on the market over the past decade.
Patheon has 8,700 employees, including more than 600 scientists in 25 locations in Europe, North America, Australia, and Asia.
The company has provided development and manufacturing services for approximately 400 clients for more than 700 products and molecules.
Through Patheon’s integrated global network of facilities, clients needs are met, which includes expertise to pharmaceutical, biotechnology and specialty pharmaceutical companies. This expertise helps clients bring drug candidates, including pre-clinical stages such as clinical trials and commercial supply.
Patheon provides a comprehensive suite of capabilities that addresses 75% of dosage forms with expertise and specialised capacity in high-potency, controlled substances, low-solubility, sterile, modified release, and softgel technologies.
Patheon OneSource
Patheon OneSource is an end-to-end development product that is simple to use, quick, and high-quality.
OneSource streamlines supply chain activities and a project manager is assigned to serve as a single point of contact for overseeing both APIs and finished products, as well as offering customers a flexible contracting process.
The offering can save up to 12 weeks, which is a significant improvement on the industry standard of a 15-month development cycle. In addition, Patheon can reduce redundancies through measures such as combined analytical activities, scientific collaboration, and parallel processing.
OneSource co-ordinates joint teams to collaborate and provide input early on in the process. Patheon has established a single harmonized quality system across its global network, ensuring it adheres to its proven track record with Right First Time and On Time Delivery, drawn on years of experience with large and small molecule APIs.
Patheon offers four specific flexible manufacturing options which are the dedicated asset model, fractional ownership model, flexible network access and the ‘condominium model.’
The company provides pharmaceutical and biotechnology companies with direct access to the expertise, quality, and full range of small or large molecule drug substance and solid and sterile dosage forms including:
Small molecule APIs and cGMP production
Process development, generic APIs and pharmaceutical intermediates portfolio
Biologics, mammalian cGMP and non cGMP manufacturing
Process and early development
Drug substance characterization
Analytical and formulation development and validation
Clinical trial material manufacturing
Late development and process and method development
Release and stability testing
Regulatory support and lifecycle management services
Improving the bioavailability of poorly soluble new chemical entities is a leading challenge in drug development. Parallel screening is a cost-effective concept for selecting a suitable drug delivery system to enhance the chance of achieving the bioavailability target in the clinic.
The challenge of taking a drug candidate from discovery through to market should not be underestimated, as there can be many hurdles to face along the path.
Early stage manufacturers of oral solid dosage forms need to be fast and flexible to generate development pathways that can cope with variable API characteristics, as well as highly potent molecules.
With the advent of combinatorial chemistry and high throughput screening, the number of poorly water soluble drug candidates has dramatically increased. The "drugability" of new chemical entities (NCEs) and life-cycle management of marketed pharmaceutical products are becoming more challenging.
For a drug product to exert its therapeutic effect, it must be soluble in an aqueous environment. This ensures that the active pharmaceutical ingredient (API) will provide sufficient concentration to induce gastrointestinal (GI) tract absorption.
The proportion of poorly soluble drug compounds in the development pipeline is on the rise, with 70% to 90% of current pipeline drugs falling in the two low-solubility classes of the biopharmaceutical classification system.
Patheon has announced it has signed a manufacturing agreement with Amgen, one of the world's leading biotechnology companies, headquartered in Thousand Oaks, CA.
Patheon has signed a strategic agreement with Grünenthal, an independent, family-owned, international research-based pharmaceutical group headquartered in Aachen, Germany, to serve as its preferred development partner for its products made using Grünenthal's innovative abuse deterrent formulation technology INTAC.
The complexity of drug product supply chains has increased over the last few years mainly due to the development of more complex chemical molecules with more synthesis steps, increasing suppliers and geographies in the chain, and reduced average production volumes.
Experts from Patheon will present on a range of industry topics at the 2015 American Association of Pharmaceutical Scientists (AAPS) Annual Meeting and Exposition from 25-29 October in Orlando.
Patheon has unveiled its new brand identity, reflecting the company's leadership position in the pharmaceutical services industry, and the difference it makes in the lives of patients.
Patheon has entered a development contract with Inhibrx, a biologic immunotherapeutic company focused on high, unmet medical needs in oncology, infectious disease and inflammatory conditions.
Patheon will showcase ways to accelerate biologic process development and funding options for biopharmaceutical programmes at the BIO International Convention in Philadelphia from 16-17 June.
Patheon has announced that Dr Marshall Crew, vice-president, global PDS scientific excellence, has been named one of the top 100 most influential people in drug development and manufacturing by the publication the Medicine Maker.
Analytical development experts will address questions about regulatory requirements, stability and shipping studies in a complimentary webinar in May, sponsored by Patheon.
Patheon will showcase its development and manufacturing services and integrated offerings at INTERPHEX in New York from Tuesday 21 to Thursday 23 April.
Patheon has closed the acquisition of IRIX Pharmaceuticals, a company that specialises in making difficult to manufacture active pharmaceutical ingredients (API) for drugs from early and late development, through to commercial launch.
Patheon has reached a definitive agreement to acquire Agere Pharmaceuticals, headquartered in Bend, Oregon, that specialises in improving absorption rate of medications (bioavailability).
Patheon has added a new filling technology that significantly reduces the time needed for formulation development and stability testing at its facility in Milton Park, UK.
An expert from Patheon will highlight the company's strategy for delivering exceptional customer experience through its integrated offerings at the Seventh Annual Global Biomanufacturing Summit.
DPx Holdings BV has announced that CEO James C Mullen will present an overview of the company and its contract development and commercial manufacturing (CDMO) business Patheon, at the 33rd Annual JP Morgan Healthcare Conference.
Patheon has announced Tom Sellig will be senior-vice president of global sales and Christopher Tama will be the new senior vice-president of global marketing.
Patheon is to showcase its biologic, small molecule API development services and manufacturing capabilities for finished dosage forms at CPhI / ICSE Worldwide from Tuesday 7 October to Thursday 9 October in Paris Nord Villepinte, France.
DPx Holdings BV has announced that it has reached a definitive agreement to buy all the shares of Gallus BioPharmaceuticals, a leading contract manufacturing company specialising in biologics and current portfolio company of Ridgemont Equity Partners.
Patheon, the pharmaceutical services business owned by DPx Holdings B.V, announced the launch of its updated programme Quick to Clinicâ„¢, making it the only CDMO to offer customers an accelerated 12-week clinical trial material programme with stability data, with a variety of flexible dosage forms.
Patheon gives global pharmaceutical, biotechnology and specialty pharmaceutical companies access to the resources and expertise to bring drug candidates from preclinical stages through clinical trials to commercial supply.
Patheon has joined with DSM Pharmaceutical Products to form businesses with an unmatched breadth of capabilities and expertise in API, biologics, development and commercial-scale manufacturing.
This week, Patheon has been showcasing the company's fully integrated early development services at the 41st Annual Meeting & Exposition of the Controlled Release Society (CRS) at The Hilton Chicago in Chicago, Illinois, US.
Patheon personnel and scientific experts will be available to meet at the CPhI/ICSE - Japan conference in Tokyo from 9-11 April to discuss how Patheon can actively support pharmaceutical and biotech companies achieve their key development and manufacturing goals.
Patheon is to specialise in high-potency at the company's Milton Park, UK, facility. Investment in early development capabilities in Europe means increased capacity for handling highly potent compounds in the early pharmaceutical development phases in the UK and then feeding into the later stage and commercialisation capabilities at a site in Bourgoin, France.
JLL Partners and Royal DSM have today announced the creation of a new company, which will be a leading global contract development and manufacturing organisation (CDMO) for the pharmaceutical industry with anticipated sales of around $2bn.
Patheon is a leading provider of contract pharmaceutical development services and commercial manufacturing. Patheon has three white papers available for download free of charge from Pharmaceutical Technology.
Patheon, a leading provider of contract development and commercial manufacturing services to the global pharmaceutical industry, today announced that it will be hosting a complimentary seminar entitled "Formulation, Funding and First-in-Man: A Stepwise Guide to Clinical Success".
Patheon, a leading provider of contract development and manufacturing services to the global pharmaceutical industry, is hosting a complimentary, half-day seminar entitled "Product Enhancement through Complex Dosage Forms: Adding Value to Products' Lifecycle Management" on June 18, 2013 at the MassBio Headquarters in Cambridge, Massachusetts.
Patheon Inc., a leading provider of contract development and manufacturing services to the global pharmaceutical industry, announced today that the company will showcase its high potency capabilities at the 2013 BIO International Convention in Chicago, Illinois on April 22 - 25, 2013, as well as at INTERPHEX 2013 in New York City on April 23 - 25, 2013.
Patheon Inc., a leading provider of contract development and manufacturing services to the global pharmaceutical industry, will be exhibiting and presenting at the 2013 Global Formulation and Drug Delivery Summit in Amsterdam, the Netherlands.
Internationally renowned pharmaceutical contract developer Patheon has released a preview of its online seminar, entitled 'Getting Your Drug through Phase I Early Development Effectively', on Pharmaceutical Technology.
Patheon, a leading provider of contract development and commercial manufacturing services to the global pharmaceutical industry, today announced plans for additional investment in its Milton Park facility.
Patheon, a leading provider of contract development and manufacturing services to the global pharmaceutical industry, announced today full year and fourth quarter results for fiscal 2012.
Patheon, a leading provider of contract development and manufacturing services to the global pharmaceutical industry, today announced that it has completed its acquisition of Banner Pharmacaps (Banner), a specialty pharmaceutical business dedicated to the research, development and manufacturing of unique gelatin-based dosage forms.