Containment Solutions for HPAPI Production
Production and handling of high-potency active pharmaceutical ingredients (HPAPI) or toxic products in gas, liquid or powder form need total product separation from the environment to protect operators.
FPS Food and Pharma Systems
Size-reduction Machines and Containment Solutions for API
Via Vandelli, 20, Como 22100, Italy
Food and Pharma Systems (FPS) develops, manufactures, and installs fine size-reduction machines, as well as containment solutions of sterile and highly toxic active pharmaceutical ingredients (HPAPI).
FPS aims to develop, design, and supply systems to improve process results for the pharmaceutical and fine chemical industries.
Containment and cleanroom solutions for safe handling of pharmaceuticals
FPS’ systems meet a wide range of client needs and requirements due to the company’s approach of discussing any needs with the end user. Topics such as protection, productivity, and quality are considered to identify the most suitable solution.
FPS’ containment product portfolio includes isolators for the highest levels of protection, such as for sterile and toxic materials. For smaller volumes, laminar flow booths are available, as well as pack-off systems, which can safely discharge weigh and pack powders.
For general applications, FPS’ local extraction arms can reduce dust generation.
FPS Food and Pharma Systems
The company also offers a variety of cleanroom solutions, which includes partitioning walls, flooring with PVC mats, and co-planar surfaces.
Micronisation for fine grinding
FPS’ fluid jet mills and mechanical mills undertake micronisation processes to ensure high-quality fine grinding. The company’s experts can determine the best configuration for a client’s needs.
FPS’ micronisation product range includes spiral jet mills, the QMill, and the PinMill. Spiral jet mill technology is suitable for particle size distribution (PSD) below 3 µm, while the QMill and PinMill are better suited for PSD between 30 µm and 100 µm.
Spiral jet mill technology achieves size reduction by accelerating particles using high-speed jet streams. The particles are then collided to get a target PSD down to D90 µm < 3 µm.
Mechanical mills reduce pharmaceutical and chemical agglomerates to fine particles. FPS’ mills include a specially designed housing with an interchangeable stator and rotor.
QMill technology acts as an alternative to mechanical. Specifically designed for pharmaceutical applications, all connections are made in compliance with current good manufacturing practice (cGMP) standards and features quick assembly and disassembly. The number of components has also been reduced to a minimum to ensure easy cleaning and validation.
The spiral jet mill and QMill series are complete with dedicated feeding systems (volumetric or gravimetric) and final powder collection and filtration units.
Isolators for HPAPI production (containment down to nanogram levels), formulation, and packaging
Production and handling of highly potent active pharmaceutical ingredients (HPAPI) or toxic gases, liquids, and powders, require isolation to protect operators and the environment. In FPS’ isolators maintain a negative pressure regime and turbulent airflow is adopted. Containment levels between 0.01µg/m³ and 10µg/m³ can be achieved, with a variety of manufacturing solutions and configurations.
Any operator accessing the interior of the isolator must do so via its glove ports or half-suit.
Containment of HPAPI Oral Solid Form activity requires high-integration with the process machines without affecting functionalities and performance. The goal is to guarantee the best use of the process machines assuring high-containment capability.
The process is kept separated by means of closed rigid walls around the formulation machines. Suitable air barriers are provided when continuous operations are requested.
Dedusting machines and powder suction units are also proposed to be integrated inside the isolators to provide a higher containment.
Isolators for sterile applications
FPS also produces isolators for sterile applications. These are available as either closed isolators or restricted access barrier system (RABS). They allow operators to avoid the use of sterile cleanrooms and reduce the sterile volume in the process. Unidirectional or turbulent airflows can be used for ventilation.
Applications for FPS’ isolators include sterility testing, aseptic filling lines for pharmaceutical or food production, vessel charging of sterile products, and sterile milling and micronisation.
Integrated decontamination systems such as vapourised hydrogen peroxide (VHP) generators are also generally used.
Multi-milling platform
FPS proposes an innovative interchangeable milling station, which is used for milling operations in research and pilot plants. It contains different technologies integrated into a single system.
About FPS Food Pharma Systems
FPS produces high-quality systems and provides support through from initial discussions of a client’s needs to full-scale mock-up. The company can help clients comply to factory acceptance tests (FAT) and standardised measurement of equipment particulate airborne concentration (SMEPAC) tests, as well as assists customers after the delivery of equipment with maintenance and installation services.
As FPS machines are constantly evolving, its technical team is available to suggest possible upgrades and improvements. FPS employs about 50 people in Italy and has a wide network of agents, which assures a global presence.
Covid-19: Swabbing Solution for Operator and Patient Safety
FPS is pleased to announce the developing of a new innovating solution for swabbing that will ensure the absolute safety of operators and patients.
FPS to Attend Next DUPHAT Tech in Dubai, 25-27 February
FPS is proud to announce its participation at DUPHAT Tech show in Dubai on 25-27 February.
Open Factory 2019: a Super Day in FPS
On Sunday 24 November, FPS took part in the initiative promoted by L'Economia, a section of the famous Italian newspaper Il Corriere della Sera, opening the doors of its renovated production plant in Fiorenzuola d'Arda to hundreds of visitors.
FPS to Attend Open Factory on 24 November
In collaboration with The Economy of ‘Il Corriere della Sera’, FPS is pleased to announce its participation in the “Open Factory” event, which will take place on Sunday 24 November from 2:00pm to 7:00pm, at the FPS operational headquarters in Fiorenzuola d’Arda (PC).
FPS to Exhibit at the 30th edition of the CPHI WW in Frankfurt
FPS is pleased to announce its participation at the 30th edition of the CPHI WW in Frankfurt, the largest trade fair in the world, which brings together over 45,000 pharmaceutical industry professionals and 2,500 exhibitors from over 150 countries.
FPS to Present Third Micronisation Workshop
FPS will launch the third edition of its micronisation seminar, which will take place on 15 October 2019 at its operational headquarter in Fiorenzuola d’Arda, France.
FPS to Appear at Open Factory Event on 24 November
FPS, in collaboration with The Economy of Il Corriere della Sera, announces its participation in Open Factory, which will take place on 24 November, at the operational headquarters of FPS, in Fiorenzuola d'Arda (PC).
FPS Proposes the Third workshop on Containment World in Rome
Taking place in Rome on 4 October, upon conclusion of the 5th edition of the HPAPI Summit, FPS will be the Gold sponsor and Speaker.
FPS to Attend HPAPI World Annual Appointment on 2-3 October
FPS and its partner Vonlanthen Group will be participating at the 5th Hpapi summit edition, Rome from 2-3 October. The event is taking place at the Hotel Eurostars Roma Aeterna.
FPS Announces Events Schedule for Final Quarter of 2019
FPS announces its presence at the most important events in the pharmaceutical field.
FPS Publishes Research on Jet Mills’ Role in Micronisation
FPS has collaborated with industry experts to research jet mill practices in the pharmaceutical industry.
Micronisation Services by FPS
FPS is an Italian company specialised in the production of containment and micronisation systems for pharmaceutical, biotech and fine chemical companies.
FPS to Attend CPHI North America, Chicago
Together with its staff, FPS will be attending the third edition of the CPHI North America fair to be held in Chicago.
FPS to participate at CIPM
FPS Food and Pharma Systems has confirmed its participation in the 57th edition of the CIPM event.
FPS will be Present at POWTECH 2019 in Nuremberg, Germany
FPS has announced that it will be attending POWTECH in Nuremberg, Germany.
FPS to Showcase at PHARMINTECH, Bologna
FPS is pleased to announce its presence at PHARMINTECH in Bologna.
FPS to Participate at PHARMACONEX, Egypt
For the second year, FPS is pleased to participate in the 7th edition of the PHARMACONEX, one of the largest gatherings in the pharmaceutical sector in Egypt and the Middle East.
FPS to Attend INTERPHEX, New York, US
FPS is proud to participate in the next edition of INTERPHEX.
FPS Announces Containment Training Day
FPS is proud to announce a new event for the containment field.
FPS Pays Particular Attention to the Mock-Up in the Design Stage
FPS is an Italian company specialised in the production of containment and micronisation systems for pharmaceutical, biotech and fine chemical companies.
Meet FPS at Events Throughout 2019
FPS has announced its presence at the following events for 2019.
See Innovative Micronisation and Containment Solutions at CPhI
FPS has announced it will be showcasing its innovations on micronisation and containment at CphI India.
FPS Workshop: Micronisation in the Pharmaceutical Field
FPS has announced a new workshop on containment and micronisation that will be held in November in Fiorenzuola d’Arda, Italy.
FPS Participates at HPAPI WORLD SUMMIT
FPS has announced it will participate at the world HPAPI summit in Basel, Switzerland.
FPS Workshop: Integration of Process Equipment in High-Containment Systems
FPS is pleased to announce a new workshop on containment and micronisation that will be held in October in Fiorenzuola d’Arda, Italy.
FPS to Attend CPhI Middle East and Africa
For the first time, FPS has confirmed its presence, in partnership with Dott.Bonapace, at CPhI Middle East & Africa.
Visit FPS at ISPE Exhibiton and Conference
Together with its local partner 1Supplier, FPS will be present at the next ISPE event.
FPS to Attend ACHEMA, Frankfurt, Germany
FPS has announced it will be attending the ACHEMA trade fair, a worldwide forum and show for the process industries.
FPS Food and Pharma Systems Events in April
FPS has announced its presence at the forthcoming 2018 INTERPHEX (International Pharmaceutical Expo) event at the Javits Center in New York City.
FPS to Attend Pharmaconex, Cairo
FPS has announced it will be attending Pharmaconex 2018, Cairo, Egypt.
Tailor-Made Containment System Match with Asepsis
FPS has announced the delivery of a complex project that combines high containment within aseptic conditions.
FPS to Open New Conference and Training Room
FPS is proud to announce the opening of its new conference and training room, which will host a number of training events in the second half of 2018.
FPS Food and Pharma Systems Events in March
FPS and its local partner Codols Technology have announced they are to attend FarmaForum, Madrid, Spain.
FPS Announces Opening of its North America Office
FPS has announced it is opening a new office in Philadelphia to support the continued growth of its business in North America.
Visit FPS at CPhI India!
FPS Food and Pharma Systems has announced it will be present at the annual appointment CPhI India in Mumbai.
FPS Food and Pharma Systems Awarded OHSAS 18001 Certification
FPS Food and Pharma Systems has received the OHSAS 18001 certification from independent company RINA.
Visit FPS at Pharmtech & Ingredients
FPS has confirmed its presence at Pharmtech & Ingredients show in Moscow.
F.P.S. Food and Pharma Systems will attend CIPM China
F.P.S. Food and Pharma Systems has announced it will be attending the 54th CIPM China in Chansha.
You are Invited to Visit FPS Food and Pharma Systems at CPhI World Wide
FPS Food and Pharma Systems will be present at the annual appointment CPhI World Wide in Frankfurt.
FPS to be Present at POWTECH
FPS Food and Pharma Systems has announced its presence at the forthcoming 2017 POWTECH event at Nürnberg Exhibition Center.
FPS to sponsor 3rd Highly Potent Active Pharmaceutical Ingredients Summit, Barcelona
FPS has announced it will be attending the 3rd Highly Potent Active Pharmaceutical Ingredients Summit in Barcelona.
FPS Food and Pharma Systems to Attend EXPOQUIMIA
FPS has confirmed its presence at Expoquimia, Barcelona.
FPS Partners With World Mountain Running Long Distance Championships, Italy
FPS has announced its official partnership with the 14th edition of the World Mountain Running Long Distance Championships, Italy.
FPS to Exhibit at EXPO PACK 2017
FPS is pleased to announce it will be exhibiting at the EXPO PACK 2017 trade fair, which takes place 13-15 June in Guadalajara, Mexico.
FPS Provides High-Containment Integrated System for Pharmaceutical Applications in India
FPS has announced delivery of a high-containment Integrated system for an Oncology plant in Bangalore, India.
FPS to Sponsor HPAPI Conference in London, UK
FPS will be attending the first Annual Formulation and Drug Delivery Congress, which will be held in London, UK, from 22-23 May 2017.
FPS to Attend COPHEX in Seoul, South Korea
FPS has announced it will be attending COPHEX, one of Korea's leading pharmaceutical and cosmetic industry exhibitions.
Visit FPS Food and Pharma Systems at PharmaCongress
FPS Food and Pharma Systems will be present at the annual PharmaCongress Production and Technology in Dusseldorf
FPS to Attend Interphex, New York
FPS has announced it will show its latest innovations in micronisation and milling technologies for pharmaceutical, cosmetic, and chemical applications at Interphex New York.
FPS Food and Pharma Systems will be present at INTERPHEX 2017 in New York
FPS Food and Pharma Systems has announced its presence at the forthcoming 2017 INTERPHEX (International Pharmaceutical Expo) event at the Javits Center in New York City.
FPS Food and Pharma Systems to Attend Asia Pharma Expo
For the first time, FPS Food and Pharma Systems and its local partner will attend Asia Pharma Expo
FPS Food and Pharma Systems to Attend the IV Farmaforum
FPS Food and Pharma Systems has announced it will be attending FarmaForum, an event for the pharmaceutical, biopharmaceutical, and laboratory technology industries.
FPS Announces Production Plant Expansions
FPS Food and Pharma Systems has announced it is expanding its production plant in Fiorenzuola d'Arda for greater flexibility and timeliness on production systems.
FPS Food and Pharma Systems Develops Software for Sterile Contained PM8 Micronising System
FPS Food and Pharma Systems has developed software, which controls equipment functionalities of a sterile micronisation system.
FPS Food and Pharma Systems to Showcase Containment and Micronisation Solutions at CPhl
FPS Food and Pharma Systems will display its innovative solutions for containment and micronisation at CPhI in Barcelona.
FPS Food and Pharma Systems
Via Vandelli, 20
Como 22100
Italy
Plant and R&D center