Patheon Contract Pharmaceutical Development Services and Commercial Manufacturing
Patheon specialises in pharmaceutical development and manufacturing services.
Active pharmaceutical ingredients (API) for the pharmaceutical sector
Patheon provides an integrated and customizable range of active pharmaceutical ingredients (API) and finished drug product services, including formulation development, clinical and commercial-scale manufacturing, packaging, and lifecycle management.
The company’s services address small and large molecule biological drugs.
Patheon is an end-to-end integrated provider, which combines scientific and regulatory expertise and specialised capabilities. This provides clients with a single outsourced provider to address complex development and manufacturing challenges.
Patheon specialises in leading product development services and commercial-scale product manufacturing.
Development and manufacturing solutions
Patheon transforms the pharmaceutical supply chain model with innovative, flexible, and customised end-to-end development, as well as manufacturing solutions that reduce complexity and shorten time-to-market.
Clients gain access to a wide range of drug substances, pharmaceutical development, and drug product solutions for large and small molecules, including an array of oral solid, sterile, and softgel dosage forms.
This provides flexibility to choose the most appropriate chemistry, manufacturing, and controls (CMC) technologies with the confidence that the programme will be delivered on time.
The company employs new business models to help clients simplify their supply chain management activities in an increasingly complex drug development industry.
Drug substance and drug product services
Patheon is organized into three distinct business units, drug substance services (DSS), pharmaceutical development services (PDS), and drug product services (DPS).
DSS is one of the top three outsourced manufacturers of highly complex biological drug substance produced in four biological API facilities. These sites are positioned to serve 70% of the market.
Patheon provides complex small molecule APIs and flexible outsourced manufacturing solutions for large molecule biologic APIs from early development through to commercial-scale production.
PDS Patheon is a leading global provider of formulation services. The company’s capabilities span the full breadth of advanced scientific services, including discovery, regulatory approval and formulation development across 40 dosage forms, as well as analytical services and life-cycle management.
DPS Patheon has developed and manufactured 20% of the top 100 drugs and 75% of the dosage forms on the market over the past decade.
Patheon has 8,700 employees, including more than 600 scientists in 25 locations in Europe, North America, Australia, and Asia.
The company has provided development and manufacturing services for approximately 400 clients for more than 700 products and molecules.
Through Patheon’s integrated global network of facilities, clients needs are met, which includes expertise to pharmaceutical, biotechnology and specialty pharmaceutical companies. This expertise helps clients bring drug candidates, including pre-clinical stages such as clinical trials and commercial supply.
Patheon provides a comprehensive suite of capabilities that addresses 75% of dosage forms with expertise and specialised capacity in high-potency, controlled substances, low-solubility, sterile, modified release, and softgel technologies.
Patheon OneSource is an end-to-end development product that is simple to use, quick, and high-quality.
- OneSource streamlines supply chain activities and a project manager is assigned to serve as a single point of contact for overseeing both APIs and finished products, as well as offering customers a flexible contracting process.
- The offering can save up to 12 weeks, which is a significant improvement on the industry standard of a 15-month development cycle. In addition, Patheon can reduce redundancies through measures such as combined analytical activities, scientific collaboration, and parallel processing.
- OneSource co-ordinates joint teams to collaborate and provide input early on in the process. Patheon has established a single harmonized quality system across its global network, ensuring it adheres to its proven track record with Right First Time and On Time Delivery, drawn on years of experience with large and small molecule APIs.
Patheon offers four specific flexible manufacturing options which are the dedicated asset model, fractional ownership model, flexible network access and the ‘condominium model.’
The company provides pharmaceutical and biotechnology companies with direct access to the expertise, quality, and full range of small or large molecule drug substance and solid and sterile dosage forms including:
- Small molecule APIs and cGMP production
- Process development, generic APIs and pharmaceutical intermediates portfolio
- Biologics, mammalian cGMP and non cGMP manufacturing
- Process and early development
- Drug substance characterization
- Analytical and formulation development and validation
- Clinical trial material manufacturing
- Late development and process and method development
- Release and stability testing
- Regulatory support and lifecycle management services
- Commercial manufacturing and packaging
- Tech transfer/scale-up management
- Risk mitigation services
How to Choose the Right Solubilisation Technology for an API
The proportion of poorly soluble drug compounds in the development pipeline is on the rise, with 70% to 90% of current pipeline drugs falling in the two low-solubility classes of the biopharmaceutical classification system.
Bridging the Gap between Early Phase Development and Commercialisation, International Pharmaceutical Industry
The challenge of taking a drug candidate from discovery through to market should not be underestimated, as there can be many hurdles to face along the path.
A Rapid Vehicle-Screening Approach for Formulating a Low-Solubility Compound into Liquid-Filled Capsules, from Tablets and Capsules
For a drug product to exert its therapeutic effect, it must be soluble in an aqueous environment. This ensures that the active pharmaceutical ingredient (API) will provide sufficient concentration to induce gastrointestinal (GI) tract absorption.
Fast and Flexible: Early Phase Manufacturing, European Biopharmaceutical Review
Early stage manufacturers of oral solid dosage forms need to be fast and flexible to generate development pathways that can cope with variable API characteristics, as well as highly potent molecules.
Formulating and Producing Tablets Containing Large, Coated Multiparticulates
Controlled-release drug delivery systems can be broadly classified as either single-unit dosage forms or multiple-unit dosage forms.
Parallel Screening, European Pharmaceutical Contractor
Improving the bioavailability of poorly soluble new chemical entities is a leading challenge in drug development. Parallel screening is a cost-effective concept for selecting a suitable drug delivery system to enhance the chance of achieving the bioavailability target in the clinic.
Formulation Strategies for Poorly Soluble Drugs
With the advent of combinatorial chemistry and high throughput screening, the number of poorly water soluble drug candidates has dramatically increased. The "drugability" of new chemical entities (NCEs) and life-cycle management of marketed pharmaceutical products are becoming more challenging.
Optimising Pharmaceutical Products Using Formulation Science, Tablets & Capsules
Approval of new drug products that treat unmet medical needs held steady or declined over the last decade.
Patheon has made an initial public offering of 30,487,805 of its ordinary sharesRead more
Patheon has announced it has signed a manufacturing agreement with Amgen, one of the world's leading biotechnology companies, headquartered in Thousand Oaks, CA.Read more
Patheon has signed a strategic agreement with Grünenthal, an independent, family-owned, international research-based pharmaceutical group headquartered in Aachen, Germany, to serve as its preferred development partner for its products made using Grünenthal's innovative abuse deterrent formulation technology INTAC.Read more
The complexity of drug product supply chains has increased over the last few years mainly due to the development of more complex chemical molecules with more synthesis steps, increasing suppliers and geographies in the chain, and reduced average production volumes.Read more
Experts from Patheon will present on a range of industry topics at the 2015 American Association of Pharmaceutical Scientists (AAPS) Annual Meeting and Exposition from 25-29 October in Orlando.Read more
Patheon will be attending the 26th Annual CPhI ICSE Worldwide conference from 13 - 15 October in Madrid.Read more
LIVIA Group has entered an agreement to acquire the Capua manufacturing facility and associated employees from Patheon.Read more
Patheon will showcase ways to accelerate biologic process development and funding options for biopharmaceutical programmes at the BIO International Convention in Philadelphia from 16-17 June.Read more
Patheon has announced that Dr Marshall Crew, vice-president, global PDS scientific excellence, has been named one of the top 100 most influential people in drug development and manufacturing by the publication the Medicine Maker.Read more
Analytical development experts will address questions about regulatory requirements, stability and shipping studies in a complimentary webinar in May, sponsored by Patheon.Read more
Patheon is investing more than $3 million to expand its Greenville, North Carolina site's stability testing capabilities.Read more
Patheon will showcase its development and manufacturing services and integrated offerings at INTERPHEX in New York from Tuesday 21 to Thursday 23 April.Read more
Patheon has closed the acquisition of IRIX Pharmaceuticals, a company that specialises in making difficult to manufacture active pharmaceutical ingredients (API) for drugs from early and late development, through to commercial launch.Read more
Patheon has reached a definitive agreement to acquire Agere Pharmaceuticals, headquartered in Bend, Oregon, that specialises in improving absorption rate of medications (bioavailability).Read more
Patheon has announced it has reached a definitive agreement to acquire IRIX Pharmaceuticals.Read more
Patheon has added a new filling technology that significantly reduces the time needed for formulation development and stability testing at its facility in Milton Park, UK.Read more
An expert from Patheon will highlight the company's strategy for delivering exceptional customer experience through its integrated offerings at the Seventh Annual Global Biomanufacturing Summit.Read more
DPx Holdings BV has announced that CEO James C Mullen will present an overview of the company and its contract development and commercial manufacturing (CDMO) business Patheon, at the 33rd Annual JP Morgan Healthcare Conference.Read more
Patheon has announced Tom Sellig will be senior-vice president of global sales and Christopher Tama will be the new senior vice-president of global marketing.Read more
Patheon is to showcase its biologic, small molecule API development services and manufacturing capabilities for finished dosage forms at CPhI / ICSE Worldwide from Tuesday 7 October to Thursday 9 October in Paris Nord Villepinte, France.Read more
DPx Holdings BV has announced that it has reached a definitive agreement to buy all the shares of Gallus BioPharmaceuticals, a leading contract manufacturing company specialising in biologics and current portfolio company of Ridgemont Equity Partners.Read more
Patheon, the pharmaceutical services business owned by DPx Holdings B.V, announced the launch of its updated programme Quick to Clinic™, making it the only CDMO to offer customers an accelerated 12-week clinical trial material programme with stability data, with a variety of flexible dosage forms.Read more
Patheon has joined with DSM Pharmaceutical Products to form businesses with an unmatched breadth of capabilities and expertise in API, biologics, development and commercial-scale manufacturing.Read more
This week, Patheon has been showcasing the company's fully integrated early development services at the 41st Annual Meeting & Exposition of the Controlled Release Society (CRS) at The Hilton Chicago in Chicago, Illinois, US.Read more
DPx Holdings BV is launching a new, US-wide operational excellence programme, called Driving Performance eXponentially (DPx).Read more
DPx Holdings BV (DPX) has donated a total of $110,000 to more than 20 hospitals and good causes around the world.Read more
Patheon is sharing a series of papers on Pharmaceutical-technology.com, targeting the early phase pharmaceutical development process.Read more
Patheon Inc is to launch the company's capabilities at FCE Pharma in Sao Paulo, Brazil, 12-14 May 2014.Read more
Patheon personnel and scientific experts will be available to meet at the CPhI/ICSE - Japan conference in Tokyo from 9-11 April to discuss how Patheon can actively support pharmaceutical and biotech companies achieve their key development and manufacturing goals.Read more
Patheon has recently received FDA approval for its Bourgoin, France site to begin manufacturing and selling drugs to the US market.Read more
Patheon is to specialise in high-potency at the company's Milton Park, UK, facility. Investment in early development capabilities in Europe means increased capacity for handling highly potent compounds in the early pharmaceutical development phases in the UK and then feeding into the later stage and commercialisation capabilities at a site in Bourgoin, France.Read more
JLL Partners and Royal DSM have today announced the creation of a new company, which will be a leading global contract development and manufacturing organisation (CDMO) for the pharmaceutical industry with anticipated sales of around $2bn.Read more
Patheon Inc is to attend Nuova Ompi - Stevanato Group's Innovation Day 2013 at the West Grand Frankfurt Hotel in Frankfurt, Germany, this week.Read more
Patheon will showcase its offerings, including non-sterile, sterile and softgel dose forms at CPhI/ICSE in Messe Frankfurt, Germany, 22-24 October.Read more
Patheon has released a free white paper entitled 'Formulating and Producing Tablets Containing Large, Coated Multiparticulates'.Read more
Patheon’s Michael Lehmann Included on PharmaVOICE 100 List of Most Inspiring People in Life Sciences Industry
The PharmaVOICE 100 award represents a broad cross section of industry sectors.Read more
Patheon to Host Complimentary Seminar – Formulation, Funding and First-in-Man: A Stepwise Guide to Clinical Success
Patheon, a leading provider of contract development and commercial manufacturing services to the global pharmaceutical industry, today announced that it will be hosting a complimentary seminar entitled "Formulation, Funding and First-in-Man: A Stepwise Guide to Clinical Success".Read more
Patheon-Sponsored Event – Product Enhancement Through Complex Dosage Forms: Adding Value to Products’ Lifecycle Management
Patheon, a leading provider of contract development and manufacturing services to the global pharmaceutical industry, is hosting a complimentary, half-day seminar entitled "Product Enhancement through Complex Dosage Forms: Adding Value to Products' Lifecycle Management" on June 18, 2013 at the MassBio Headquarters in Cambridge, Massachusetts.Read more
Patheon Inc., a leading provider of contract development and manufacturing services to the global pharmaceutical industry, announced today that the company will showcase its high potency capabilities at the 2013 BIO International Convention in Chicago, Illinois on April 22 - 25, 2013, as well as at INTERPHEX 2013 in New York City on April 23 - 25, 2013.Read more
Patheon Inc., a leading provider of contract development and manufacturing services to the global pharmaceutical industry, will be exhibiting and presenting at the 2013 Global Formulation and Drug Delivery Summit in Amsterdam, the Netherlands.Read more
Internationally renowned pharmaceutical contract developer Patheon has released a preview of its online seminar, entitled 'Getting Your Drug through Phase I Early Development Effectively', on Pharmaceutical Technology.Read more
Patheon Announces First Phase of Additional Investment in Milton Park, UK Facility to Expand Early Development Capabilities in Europe
Patheon, a leading provider of contract development and commercial manufacturing services to the global pharmaceutical industry, today announced plans for additional investment in its Milton Park facility.Read more
Patheon, a leading provider of contract development and manufacturing services to the global pharmaceutical industry, announced today full year and fourth quarter results for fiscal 2012.Read more
Patheon, a leading provider of contract development and manufacturing services to the global pharmaceutical industry, today announced that it has completed its acquisition of Banner Pharmacaps (Banner), a specialty pharmaceutical business dedicated to the research, development and manufacturing of unique gelatin-based dosage forms.Read more
4721 Emperor Blvd Suite 200
Durham, NC 27703-8580
United States of America
Wiltshire SN3 5BZ
7F Wakamatsu Building, 3-3-6
Nihonbashi Hon-cho, Chuo-ku,