Neopharma Pharmaceutical Plant, Abu Dhabi
Neopharma opened a new pharmaceutical plant in Abu Dhabi, United Arab Emirates, in July 2003.
Metrohm
Titration, Voltammetry and Ion Chromatography Services
Metrohm is the global market leader in the fields of titration and voltammetry, and one of the leading innovators in ion chromatography, online analysis and laboratory automation.
Metrohm is the only company providing all relevant ion analysis technologies under one roof: potentiometric and Karl Fischer titration, voltammetry and ion chromatography, as well as pH, ion, conductivity and oxidation stability measurements. Additionally, we offer instrument software, method-specific software packages, and peripheral units, as well as a full range of systems for dosing and liquid handling.
Customised analysis for the pharmaceutical industry
With regard to the quality and safety of drugs, authorities worldwide set high standards for the pharmaceutical industry. These are documented in pharmacopoeias in the form of official collections of recognised pharmaceutical rules. As legal tools of consumer protection, they ensure that drugs are used safely.
To ensure these high quality and safety standards, reliable instruments and methods are needed.
Instruments for titration, ion chromatography and pH measurement
As a leading manufacturer of instruments for titration, ion chromatography and pH measurement, Metrohm is aware of these challenges. For this reason, Metrohm offers you not only the latest instruments, but complete solutions for very specific analytical issues.
Your Metrohm contacts are competent specialists, who will develop customised applications and provide you with professional support in all matters of regulatory compliance.
Discover what solutions Metrohm is able to offer the pharmaceutical sector, and you in particular, to ensure the quality and safety of your products.
Intelligent titrator without reliability gaps
Thanks to its modular concept, the Titrando system can easily be adapted to any application. It meets the requirements of FDA regulation 21 CFR Part 11, irrespective of its use as stand-alone titrator in combination with 840 Touch Control, PC Control or tiamo.
The advantages at a glance:
- Brainy dosing elements with certification
- The iTrodes – intelligent electrodes
- STAT titration with tandem dosing
- Flexibility – from the individual instrument to the fully automated system
- Sample preparation at the touch of a button
Automatic sample preparation instruments
With instruments of the Robotic Soliprep family, neither deviant results nor time-consuming manual routines are an issue. The solid substance is simply weighed out and placed in the sample rack – all the rest is done fully automatically.
Depending on the model selected, different steps can be combined – including the direct connection to a chromatograph or the titration of the homogenised sample.
Ion chromatography systems
Ion chromatography is the method of choice to determine active ingredients, excipients and traces of impurities and metabolites in the form of organic and inorganic ions or polar substances in a number of pharmaceuticals, pharmaceutical solutions or body fluids. In particular, Metrohm ion chromatography systems handle demanding analytical challenges such as the determination of impurities in pharmaceuticals, active pharmaceutical ingredients and pharmaceutical solutions.
Metrohm has taken ion chromatography to an entirely new level. The 850 Professional IC is the first ion chromatography system made up of intelligent components.
Measuring stand for voltammetric and polarographic determinations
Voltammetry also enables organic compounds to be determined with a high degree of sensitivity. This makes it possible to analyse many active pharmaceutical ingredients according to USP<801>.
The 797 VA Computrace is a modern measuring stand that allows voltammetric and polarographic determinations to be performed.
Some application examples:
- Fe(II) in iron sucrose injection solution according to USP-NF
- Thimerosal in eye or nose drops, vaccines and cleaning solutions for contact lenses according to USP-NF
- Heavy metal impurities in pharmaceutical products
Metrohm is exclusively represented in more than 80 countries, more than 40 of which have their own subsidiaries. This guarantees a tight network for sales and service.
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Novartis Vaccine Manufacturing Facility, North Carolina
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University of Maryland Biopark
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Pronova Biopharma Pharmaceutical Production Facility
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Norwich Pharmaceuticals Norwich Facility
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Genzyme Science Center Framingham, Massachusetts, USA
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Pharmstar Pharmaceuticals Plant, Rocky Mount, North Carolina
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Sanofi Pasteur Vaccine Plant, Val De Reuil, France
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Merck And Co Vaccine Facility, Carlow, Ireland
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Cipla Medpro Pharmaceuticals, South Africa
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Rentschler Biotechnologie, New Manufacturing Capacity
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Biopolis Biomedical Research Hub, Buona Vista
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Genentech Cell Culture Plant No 2 Expansion
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Shanghai CP Guojan API Production Suite, Shanghai
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Bristol-Myers Squibb – Clinical Supplies Manufacturing
Bristol-Myers Squibb (BMS) has been undergoing much the same rationalisation process as many large pharmaceutical compan
Boehringer Ingelheim Pharmaceutical R&D Building, Biberach, Germany
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Quality Chemical Industries – HIV Drug Plant
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Novartis Biomanufacturing Plant
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Bristol-Myers Squibb
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Abbott Laboratories Biotech Facility, Puerto Rico
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GlaxoSmithKline Vaccine Manufacturing Facility, Tuas
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Bidachem Active Pharmaceutical Ingredients Plant, Bergamo
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Medimmune, Biologics Manufacturing Facility
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Sanofi Pasteur Vaccine Production Plant, Swiftwater, Pennsylvania
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Roche Bulk Active Ingredient Manufacturing Facility, Florence, SC
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Genzyme Biomanufacturing Plant
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KBI Biopharma, North Carolina Center For Biomanufacturing, Durham, North Carolina
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Cortex Biotech Facility, Missouri
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Chengdu Vaccine Plant
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Bayer Healthcare Pharmaceuticals Plant, Snohomish County, Washington State
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Shanghai Roche Pharmaceuticals, Shanghai
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Vetter Pharma-Fertigung, Contract Manufacturing Facility, Ravensburg
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Roche Biotechnology Plant, Basel
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Genzyme Manufacturing Expansion, Waterford
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Biosite HQ and Manufacturing Campus, Mera Misa, California
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Novo Nordisk Plant Expansion Tianjin
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Novoseven Facility, Hillerød
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Eli Lilly Biotech Pilot Plant, Indianapolis
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Biolex Therapeutics Facility Expansion, Pittsboro, North Carolina
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Hovione Manufacturing Plant, Loughbeg, County Cork
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Cook Pharmica Biotechnology Plant
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Merck Vaccine Plant, Durham, NC, USA
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Stirling Pharma Pharmaceutical Production
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Elan Pharma Secondary Pharmaceutical Facility
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Roche Diagnostics PCR Diagnostic Kits
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Centocor Biopharmaceutical
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AstraZeneca Symbicort Production Facility, Dunkirk
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Genentech Manufacturing Facility (NIMO)
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Bavarian Nordic Smallpox Vaccine Facility
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Serologicals Corporation Biotech Production Plant
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Eli Lilly Humalog Manufacturing Facility, Carolina
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Novo Nordisk
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Merck Sharpe & Dohme Formulation Plant
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Ferring Pharmaceuticals
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Lonza Biotec
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Aventis Recombinant
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Schering-Plough Production and R&D Facilities
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Boehringer Ingelheim
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MSD Biologics Advanced Biologics Centre
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VaxGen Biopharmaceutical Manufacturing Plant
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Baxter BioPharma Solutions Parenteral
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AstraZeneca Biopharmaceutical Manufacturing
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Lonza Biologics Plant Expansion
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Biogen Idec Pharmaceutical Production Facility
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Boehringer Ingelheim Active Ingredients Plant
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Novartis Diovan Manufacturing Plant, Schweizerhalle, Switzerland
In September 1999 Novartis opened a new pharmaceutical production facility at the Schweizerhalle site near Basel, Switzerland.
Rohner Custom Synthesis Plant
In March 1999 Rohner AG began the construction of a new state-of-the-art pharmaceutical facility at its existing site at
Amgen Process Development Facility
Bothell is the site of a process development facility owned by the pharmaceuticals firm Immunex (now owned by Amgen).
Achillion Pharmaceuticals Biotech Facility
Achillion Pharmaceuticals was founded in February 2000 as one of the largest biotech start-ups in the USA.
Amgen Pharmaceutical Manufacturing Facility
West Greenwich, Rhode Island, US, is the site of a new pharmaceutical manufacturing facility dedicated to the production
ChemSyn (Aptuit) Pharmaceutical Manufacturing Plant
ChemSyn Laboratories (now Aptuit), a leading producer of anti-cancer bulk pharmaceuticals and other high potency chemica
Novartis’ API Plant in Grimsby, West Yorkshire, UK
Novartis Pharmaceuticals' active pharmaceutical ingredients (API) plant complex in Grimsby, West Yorkshire, was first established in 1951.
Janssen Pharmaceutica’s Pharmaceutical Plant, Geel, Belgium
Johnson & Johnson (J&J) subsidiary Janssen Pharmaceutica decided to build a new pharmaceutical plant in Geel in Belgium in 1998.
MSD’s Manufacturing Plant Expansion, Ballydine Co Tipperary, Ireland
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Bayer Corporation Biotechnology Plant, Berkeley, California, US
In August 2000, the Bayer Corporation was granted permission by the city of Berkeley to develop an additional 14 acres s
AstraZeneca’s Bulk Pharmaceutical Purification Plant, Guayama, Puerto Rico
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GE Healthcare Pharmaceutical Manufacturing Plant, Shanghai, China
In 2000, Nycomed Amersham announced it would open a new pharmaceutical plant in Shanghai on 27 October.
ImClone Systems Biopharmaceutical Plant, New Jersey, US
In January 2000, ImClone Systems began construction of a new 100,000ft² biopharmaceutical manufacturing facility in Branchburg, New Jersey.
AstraZeneca Pharmaceutical Manufacturing Plant, Wuxi, Shanghai, China
In early 2001, AstraZeneca inaugurated a pharmaceutical plant in the Wuxi region of northeastern China.
Daiichi Sankyo Company, Pharmaceutical Plant, Beijing, China
In June 2000, Daiichi Sankyo Company opened a new pharmaceutical plant in Beijing.
Pfizer’s Bulk Pharmaceuticals Facility, Tuas, Singapore
The large-scale pharmaceutical facility in Tuas, Singapore, is Pfizer's first manufacturing facility in the country.
Glaxo Wellcome Anti-Infective Drugs Plant, Suzhou, China
In 1998, Glaxo Wellcome made an investment in a production facility in Suzhou in the eastern Chinese province of Jiangsu.
Trygg Pharma’s Seal Sands Bulk Pharmaceuticals Facility, Teesside, UK
In April 2000, Lundbeck Pharmaceuticals was awarded contracts for the construction of a bulk pharmaceutical facility in Seal Sands, Teesside, UK.
Roche Vitamins and Minerals Premix Plant, Republic of South Africa
Hoffman La Roche completed the first phase of construction for a vitamins and minerals premix plant at Isando, Republic of South Africa, in June 2002.
Protchem Industries Derivatives Plant, Chennai, India
In 1999, construction began on a derivatives plant for Protchem Industries.
CSL Recombinant Proteins Production Plant, Melbourne, Australia
The CSL Parkville facility has undergone several phases of expansion since 1997 when it was first opened. The production facilities have been expanded three times.
Novo Nordisk Insulin Cartridge, Chartres, France
Novo Nordisk is upgrading the insulin production plant at its facility in Chartres, Eure-et-Loir region, France. The Dan
Roche Vitamin Plant, Taishan, Shanghai
Roche's latest vitamin plant is located in Taishan, Shanghai, which is in the northeastern part of the Peoples' Republic of China.
Lonza Niacinamide Production Facility, Iksan, South Korea
Lonza Fine Chemicals and Specialties put a production facility for niacinamide into operation in 1997 following a joint venture (JV) agreement with the Guangzhou Pesticide Factory.
DSM Premix Vitamin Plant, Jalisco, Mexico
Hoffman La Roche built a vitamin premix plant in 2000 at El Salto in Jalisco, Mexico, to expand its operations in the premix vitamin market.
GlaxoSmithKline Manufacturing and Packaging Plant, Zebulon, NC
In 1999, UK-based pharmaceuticals company Glaxo Wellcome instigated a project to expand its 652,000ft² manufacturing and packaging plant in Zebulon, NC.
Metrohm AG
Oberdorfstrasse 68
9101 Herisau
Other
Switzerland
- +41 71 353 8585
- +41 71 353 8901
- info@metrohm.com
- pharma.metrohm.com
- www.metrohm.com
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